February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
119 citations
,
August 2010 in “Journal of Investigative Dermatology” Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.
31 citations
,
January 2014 in “The Scientific World JOURNAL” Eclipta prostrata extract protects skin cells from UVB damage and has strong antioxidant properties.
2 citations
,
September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes.
March 2026 in “Chemical Engineering Journal” The hydrogel helps heal diabetic wounds by combining antibacterial, antioxidant, and immune-boosting effects.
207 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
189 citations
,
May 1999 in “Microscopy Research and Technique” Neurotrophins, especially NGF, are crucial for pain development and management.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
32 citations
,
June 2021 in “Frontiers in Pharmacology” The hydrogel speeds up burn wound healing and promotes tissue regeneration.
24 citations
,
April 2013 in “PLOS ONE” TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
18 citations
,
July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
11 citations
,
August 2023 in “Burns” Nerve growth factor helps improve healing time and scar quality in burn wounds.
9 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
8 citations
,
August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
7 citations
,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
6 citations
,
October 2024 in “Frontiers in Bioengineering and Biotechnology” A special hydrogel helps stem cells heal wounds better by boosting growth factors.
6 citations
,
December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
5 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
3 citations
,
September 2024 in “The FASEB Journal” Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.
3 citations
,
January 2020 in “PubMed” Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
2 citations
,
July 2024 in “Bioengineering” PRF lysates reduce inflammation in cancer cells and boost immune response in healthy oral cells.
2 citations
,
January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
1 citations
,
April 2025 in “Frontiers in Medicine” New insights into skin damage from UV exposure suggest potential treatments, including targeting specific RNAs and combining therapies for better outcomes.
1 citations
,
January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
1 citations
,
January 2010 in “Acta Chirurgica Latviensis” Inflammation in psoriasis may trigger antimicrobial peptides and cell death.
Tropical herbs have potential for cosmetics but need more research and standardization.
February 2026 in “Exploration” Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
A comprehensive human skin cell atlas was created to better understand skin biology and disease.