January 2026 in “Journal of Dermatological Science” DcR3 helps heal wounds and regrow hair by changing macrophages to a repair-focused type.
July 2024 in “Journal of Investigative Dermatology” Glutamine helps macrophages reduce inflammation and improve wound healing.
228 citations
,
June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
17 citations
,
June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
118 citations
,
April 2020 in “Stem Cell Research & Therapy” IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.
December 2025 in “Frontiers in Immunology” Restoring nerve-macrophage communication may help treat autoimmune diseases.
175 citations
,
December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
September 2025 in “Plants” Juniperus morrisonicola wood essential oil has strong anti-inflammatory and antifungal properties.
12 citations
,
September 2022 in “Frontiers in Immunology” Soluble CD83 speeds up wound healing and reduces scarring.
8 citations
,
August 2021 in “Aging” Berberine may reduce prostate enlargement by blocking inflammation.
February 2023 in “Research Square (Research Square)” Applying certain vesicles from umbilical cord stem cells helps heal skin wounds in diabetic mice by reducing cell death and inflammation.
6 citations
,
April 2025 in “Plastic and Aesthetic Research” Biomaterial characteristics can influence macrophages to promote healing and improve tissue regeneration.
1 citations
,
September 2025 in “Frontiers in Immunology” Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
101 citations
,
July 1998 in “Journal of Investigative Dermatology” UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
45 citations
,
January 2021 in “Drug Delivery” The study developed cepharanthine-loaded nanoparticles coated with macrophage membranes (MM-CEP/NLCs) to treat acute lung injury (ALI) by targeting lung inflammation sites. This biomimetic approach utilized the natural targeting ability of macrophages, resulting in enhanced drug accumulation, sustained release, and improved biocompatibility. In vivo experiments in mice showed that MM-CEP/NLCs significantly reduced ALI severity by decreasing lung water content, histopathological damage, and inflammatory markers such as TNF-α and IL-6. The study concluded that MM-CEP/NLCs could be a promising treatment for lung inflammation due to their effective targeting and therapeutic efficacy.
36 citations
,
March 2014 in “Annals of the Rheumatic Diseases” Activating liver X receptors can reduce fibrosis by stopping certain immune cells from releasing harmful proteins.
25 citations
,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
15 citations
,
March 2023 in “BioMed” MIS-A is a severe complication after COVID-19, mostly in young black males, needing more research and awareness.
4 citations
,
September 2023 in “Stem cell research & therapy” Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
44 citations
,
March 2015 in “PLOS ONE” Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
Mechanical surface cues can control macrophage behavior for better immunotherapy and tissue healing.
79 citations
,
January 2019 in “International Journal of Molecular Sciences” Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
29 citations
,
September 2018 in “Journal of the American Heart Association” EP 2 receptor is essential for heart repair by helping macrophages work properly.
The hydrogel helps bone growth and healing in jaw and facial defects.
90 citations
,
October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
January 2025 in “Fìzìologìčnij žurnal” PDRN may reduce inflammation and complications in revision rhinoplasty for patients with high fibrinogen levels.
254 citations
,
March 2023 in “Advanced Science” The hydrogel helps heal diabetic wounds faster by reducing inflammation.
6 citations
,
November 2023 in “Chinese Medicine” Xinyang Tablet improves heart function in sepsis by reducing inflammation.
9 citations
,
October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Microglia are essential for zebrafish brain repair by controlling inflammation.