April 2020 in “The FASEB Journal” Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.
18 citations
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March 2024 in “Frontiers in Pharmacology” Natural plant products like Proanthocyanidins and curcumin may help treat ischemic stroke by reducing inflammation.
1 citations
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May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
1 citations
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April 2021 in “Journal of Cardiovascular Pharmacology” Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.
November 2025 in “Journal of Microbiology and Biotechnology” Botulinum toxin type A and platelet-rich plasma together boost hair growth by activating specific growth pathways.
November 2024 in “Research Square (Research Square)” Moracin M boosts hair growth by activating key pathways and promoting cell growth.
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
January 2026 in “Journal of Contemporary Medicine” Vitamin D may help prevent or reduce hair loss after COVID-19.
12 citations
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November 2024 in “International Journal of Molecular Sciences” Hydroxytyrosol helps reduce liver injury by blocking certain inflammation pathways.
7 citations
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March 2022 in “International Journal of Molecular Sciences” FGF21 can help reduce skin inflammation caused by C. acnes.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
48 citations
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April 2023 in “Aging Cell” Targeting cellular senescence may improve skin aging and disorders.
July 2025 in “Journal of Investigative Dermatology” Monocyte-derived dendritic cells play a key role in UVB-induced skin sensitivity and inflammation.
October 2024 in “Stem Cell Research & Therapy” CGF therapy may effectively treat psoriasis by reducing inflammation.
January 2024 in “Research Square (Research Square)” Traditional Chinese medicine may help treat ischemic stroke by targeting specific genes and pathways.
April 2017 in “Journal of Investigative Dermatology” Cow milk sugars increase fat production and inflammation in skin oil cells.
10 citations
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January 2024 in “Heliyon” Dexpanthenol helps protect the heart from damage by reducing inflammation and stress.
58 citations
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March 2019 in “Frontiers in Pharmacology” Wedelolactone may help treat lung fibrosis by reducing inflammation and lung damage.
56 citations
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November 2012 in “Endocrinology” Vitamin D receptor is essential for proper skin healing after injury.
9 citations
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October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Microglia are essential for zebrafish brain repair by controlling inflammation.
1 citations
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June 2025 in “Scientific Reports” Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
November 2025 in “Journal of Investigative Dermatology” TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.
1 citations
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January 2025 in “American Journal of Translational Research” PPARα agonists may help treat alopecia areata by reducing inflammation.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Cancer treatment drugs can cause permanent hair loss by damaging hair follicle stem cells, but a specific inhibitor might reverse this effect.
7 citations
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May 2025 in “Journal of Biomedical Science” Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.
8 citations
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March 2023 in “PubMed” JAK inhibitors show promise in treating difficult skin diseases.
6 citations
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June 2020 in “Journal of Drugs in Dermatology” PRP can help regrow hair in people with alopecia.
2 citations
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June 2024 in “JAAD reviews.” Some drugs can cause permanent hair loss, though it's rare.
June 2026 in “Saudi Medical Horizons Journal” Janus kinase (JAK) inhibitors are a promising treatment for inflammatory and autoimmune skin diseases like atopic dermatitis, alopecia areata, and vitiligo, due to their ability to target the disrupted JAK-STAT signaling pathway. Clinical research supports the effectiveness of both topical and oral JAK inhibitors, such as ruxolitinib cream and oral agents like abrocitinib, baricitinib, and upadacitinib, in reducing inflammation and itching in atopic dermatitis. For alopecia areata, baricitinib, ritlecitinib, and deuruxolitinib offer hope for severe cases. In vitiligo, topical ruxolitinib shows potential in restoring facial pigment. While generally well-tolerated, these treatments require ongoing safety monitoring due to risks like infections and cardiovascular issues. The review emphasizes the need for further research to enhance long-term safety and patient selection.