research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
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research A Perspective on RNAi-Based Biopesticides
RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research Smoking and the skin
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2
Cepharanthine and Trifluoperazine are effective against SARS-CoV-2.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Studying the genetic predisposing factors in the pathogenesis of acne vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Oxygen, Metabolism, and Regeneration: Lessons from Mice
Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
research EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management
The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
research Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding
Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
research Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease
Researchers found two new genetic variants linked to Alzheimer's disease.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Accelerated Wound Healing Using Nanoparticles
Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
research New small molecules in dermatology: for the autoimmunity, inflammation and beyond
New small molecule drugs show promise in treating complex skin diseases but need more safety research.
research Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds
ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research “MATH+” Multi-Modal Hospital Treatment Protocol for COVID-19 Infection: Clinical and Scientific Rationale
The MATH+ protocol aims to improve COVID-19 outcomes using a combination of specific treatments.
research Inhalation therapy for repairing damaged elastin fibers and decelerating elastinolysis in chronic obstructive pulmonary disease
Inhalation therapy may repair and protect elastin in the lungs of COPD patients.
research The impact of biomaterial characteristics on macrophage phenotypes in tissue engineering: a review
Biomaterial characteristics can influence macrophages to promote healing and improve tissue regeneration.
research Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways
Traditional Chinese Medicine and biomaterials help heal chronic wounds by targeting multiple pathways.
research Sustainable applications of phytochemicals and nutritive components derived from selected underutilized seeds: A review [pdf]
Underutilized seeds like jackfruit, Indian almond, and tamarind have valuable nutrients and compounds that can be used sustainably in various industries.
research Skin biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Hormones
Hormones are crucial for regulating body functions and imbalances can lead to health issues.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2
YAP1 helps fat cell formation by influencing the Hippo pathway.
research miR-29 is an important driver of aging-related phenotypes
miR-29 is a key factor that accelerates aging.