April 2014 in “The FASEB Journal” Testosterone reduces knee movement, while flutamide and finasteride increase it.
January 2019 in “11th World congress for hair research” 11 citations
,
June 1979 in “British Journal of Dermatology” The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.
43 citations
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July 2003 in “Andrology” Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
11 citations
,
January 2010 in “Springer eBooks” 10 citations
,
May 2021 in “Psychoneuroendocrinology” Testosterone levels aren't important for depression in men, but some other hormones might affect certain symptoms.
36 citations
,
June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
18 citations
,
October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
5 citations
,
January 2025 in “Science Advances” 5α-reductase 2 is crucial for stress response in male rats.
416 citations
,
September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
14 citations
,
December 2010 in “Seminars in Oncology” Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
April 2019 in “Journal of the Endocrine Society” A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
June 2025 in “Skin Research and Technology”
58 citations
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January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
2 citations
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July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain gut bacteria can lower androgen levels in male mice.
8 citations
,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
July 2022 in “Journal of Investigative Dermatology” Skin produces different hormones depending on body part and sex, and a new method can measure them.
August 2024 in “International Journal of Molecular Sciences” Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
8 citations
,
January 2012 in “General and Comparative Endocrinology” 5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.
19 citations
,
September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
January 2004 in “Anticancer Research” Long-term antiandrogen use may increase aggressive prostate cancer risk.
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
20 citations
,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
May 2021 in “The FASEB Journal” The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
Cyproterone acetate is used for topical treatment of diseases dependent on male hormones.
3 citations
,
February 2025 in “Endocrine” Confirm testosterone levels with advanced tests to avoid unnecessary procedures.
10 citations
,
March 1999 in “Comparative Haematology International” Androgens increase EPO production, finasteride doesn't significantly impact it.
March 2014 in “The Journal of Urology” Finasteride increases CD8+ T cells in BPH tissues.
2 citations
,
March 2000 in “CRC Press eBooks”