21 citations
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December 1977 in “Journal of pediatric surgery” Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
February 2024 in “IntechOpen eBooks” Myo-inositol-based treatments greatly improve pregnancy chances for women with PCOS.
A 10-year-old girl's symptoms improved after surgery to remove a benign adrenal tumor.
1 citations
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November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
March 2016 in “The Journal of Urology” The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
4 citations
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September 2010 in “Medical Hypotheses” October 2016 in “Journal of Case Reports” A rare ovarian tumor can occur without causing male-like symptoms.
1 citations
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January 2022 in “IntechOpen eBooks” Different PCOS types respond uniquely to infertility treatments, with some having lower pregnancy rates and higher risks of complications.
June 2025 in “General medicine and Clinical Practice” Lifestyle changes improve symptoms and fertility in hyper-androgenic women.
6 citations
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January 2010 in “Case Reports” A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
20 citations
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March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
June 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
December 2015 in “Endocrinology and Metabolic Syndrome” November 2024 in “Future Science OA” A rare benign ovarian tumor was found in a pregnant woman, but both mother and baby remained healthy.
94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
2 citations
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January 2014 in “International Journal of Endocrinology” Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.
2 citations
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January 2025 in “JBRA” Age is more important than BMI for IVF success in women with infertility and PCOS.
32 citations
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January 2010 in “Journal of Korean Medical Science” A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.
September 2018 in “Translational andrology and urology” MOTILIPERM may help treat male infertility by reducing stress in cells.
21 citations
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December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.
1 citations
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December 1970 in “European journal of endocrinology” Reversed sequential therapy with cyproterone acetate was effective for treating women with hirsutism and related conditions.
104 citations
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May 2019 in “F1000Research” Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.