research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
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210-240 / 1000+ results research Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
research Aging of hair follicle stem cells and their niches
Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
research Aging Skin Microbiology
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research THE CONTROL OF SOME HORMONES RELATING TO CUTANEOUS AGING: MECHANISMS, MANIFESTATIONS, AND MANAGEMENT
Hormones play a key role in skin aging, with estrogen and testosterone declines affecting skin health.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy
PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
research The Effects of an Oral Supplementation of a Natural Keratin Hydrolysate on Skin Aging: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Study in Healthy Women
Taking natural keratin supplements improved skin, hair, and nails in women.
research Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices
A diabetes-informed approach is essential for safe and effective skin rejuvenation treatments in diabetics.
research Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Homoeopathic Perspectives on the Pathophysiology and Treatment of Skin Aging
research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model
Transplanted hair follicle stem cells can heal damaged rat intestines.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research 364 Mechanical forces of human dermal fibroblasts significantly decrease with age
Skin cell strength decreases significantly as we age.
research Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging
The α-MSH-MC1R-cAMP pathway does not protect skin cells from UVA damage.
research Study on Antioxidants and Growth Factors in the Treatment of Alopecia with Injectables
Antioxidants and growth factors may help treat hair loss when combined with LED and Laser therapy.
research Microneedling and Oral Replacement of Collagen as Strategies for Skin Rejuvenation
Microneedling with oral collagen improves wrinkles better than microneedling alone.
research Platelet-Rich Plasma and Genital Rejuvenation.
Platelet-rich plasma may be effective for genital rejuvenation and deserves more research.
research Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models
Araliadiol may help reduce skin aging and inflammation without killing cells.
research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Targeting cellular senescence may improve skin aging and disorders.
research Exploration of Natural Adsorbents for Applications in Pollution-Reducing Cosmetic Formulations
Natural adsorbents in cosmetics can significantly reduce skin and hair pollution.
research Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters
Exosomal miRNAs from stem cells can help improve skin health and delay aging.
research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research Effects of UV Induced-Photoaging on the Hair Follicle Cycle of C57BL6/J Mice
UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.
research Hair Follicles as a Critical Model for Monitoring the Circadian Clock
Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.