59 citations
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November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
9 citations
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January 2018 in “BioMed Research International” Tetrahydroxystilbene Glucoside may help prevent hair loss by blocking certain pathways that lead to cell death.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
5 citations
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January 2015 in “Current problems in dermatology” The document provides a practical guide for diagnosing and treating various types of hair loss.
3 citations
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June 2017 in “Methods” Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
January 2016 in “SpringerBriefs in bioengineering” Genetic defects and UV radiation cause skin damage and aging.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
52 citations
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November 2006 in “International Journal of Cosmetic Science” Different types of wrinkles need specific treatments.
1 citations
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September 2025 in “Journal of Cosmetic Dermatology” The framework suggests sun protection, retinoids, and antioxidants to improve skin longevity.
80 citations
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April 2006 in “Clinical Interventions in Aging” Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
36 citations
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August 2022 in “Frontiers in Cell and Developmental Biology” Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
29 citations
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October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
January 2025 in “Health engineering.” Combining stem cells and organoids could improve skin regeneration treatments.
October 2024 in “Current Issues in Molecular Biology” Platycladus orientalis leaf extract helps hair grow by activating certain proteins.
33 citations
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April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
2 citations
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May 2023 in “Life” Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
February 2026 in “Preprints.org” New therapies and personalized approaches improve wound healing and patient quality of life.
July 2025 in “Burns & Trauma” 3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
2 citations
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October 1997 in “Dermatologic Clinics” The document concludes that advancements in hair restoration surgery have led to more natural results and patient satisfaction, with hope for future improvements in treatment.
1 citations
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August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
242 citations
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February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
156 citations
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December 2012 in “Cell Stem Cell” TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
59 citations
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June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
28 citations
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December 2013 in “British Journal of Oral & Maxillofacial Surgery” The document concludes that understanding the anatomical changes of the ageing face is important for effective rejuvenation treatments.
22 citations
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November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
18 citations
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January 2017 in “Dermatologic Surgery” Combining cosmetic procedures with lifestyle changes improves antiaging results.
9 citations
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February 2014 in “Tissue Engineering and Regenerative Medicine” Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.
6 citations
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March 2019 in “Dermatologic surgery” Chilled ATPv-supplemented saline best preserves hair grafts' key genes.