research Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway
Blocking the HEDGEHOG-GLI1 pathway can reduce keloid growth and may be a potential treatment.
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840-870 / 1000+ results research Three-dimensional analysis of intraepidermal nerve fibres and Langerhans cells in keloids with a focus on pruritus
Itchy keloids on the chest are linked to more nerve fibers and substance P.
research Efficacy of Punch Excision Combined With Superficial X‐Ray for the Treatment of Keloids: A Single‐Center Retrospective Study
Combining punch excision with superficial X-ray effectively improves keloid scars safely.
research NEDD4 Transcript Variant 3 and IGF-1 as Molecular Markers in the Development and Prognosis of Keloids
High levels of NEDD4-TV3 and IGF-1 may predict and contribute to keloid formation.
research 016 Anesthetics Prior to Keloid Injections: A Painless Approach
Using lidocaine before keloid injections makes the treatment more comfortable for patients.
research 861 Association between keloids and atopic dermatitis: a cross-sectional study at a tertiary care center
Keloids are strongly linked to atopic dermatitis and other health issues.
research A Prospective Study of Patients Presenting With Pre-sternal Keloids
Pre-sternal keloids are more common in males and can be effectively treated with injections, though recurrences may need more treatment.
research The role of retinoids in the management of cutaneous conditions in blacks
Retinoids help manage skin conditions in black individuals.
research Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
research Pigmentary disorders in black skin
The argon gas-based cryotherapy effectively reduced keloid scars but caused some hypopigmentation and had a recurrence rate, especially in Afro-American patients.
research A clinical study of geriatric dermatoses
Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
research Skin Problems of Blacks
Black patients have unique skin conditions that require specific knowledge for proper treatment.
research Local Injection of Triamcinolone Acetonide: A Forgotten Aetiology of Cushing’s Syndrome
Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.
research Krox20 expression in abnormal scars: An immunohistochemical study
Krox20 overexpression in fibroblasts may play a role in abnormal scar formation and could be a target for new treatments.
research Photoepilation: a potential threat to wound healing in a mouse
Photoepilation may disrupt normal wound healing and increase the risk of scars.
research Clinical Snippets
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research Support for dermatological research in Sub‐Saharan Africa: insights from African hair and skin research programs
The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.
research JCD Editorial September 2021
The editorial stresses the importance of COVID-19 vaccination and ongoing contributions to the journal.
research Suppression of fibroblast proliferation and lysyl hydroxylase activity by minoxidil.
Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
research Dermatology in black skin
Black skin needs more focused dermatology research for better diagnosis and treatment.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades
miR-3606-3p reduces skin fibrosis by blocking key signaling pathways.
research [Methotrexate to treat SAPHO syndrome with keloidal scars].
Methotrexate effectively managed SAPHO syndrome symptoms when other treatments failed.
research Skin Manifestations in Individuals of African or Asian Descent
People of African or Asian descent have unique skin issues that need special care.
research 1270 Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
research Dermatological aspects of gender affirming medical treatment in transgender and gender diverse people: A systematic review
Transgender individuals may face specific skin issues during gender-affirming treatments, needing personalized care.
research TRANSPLANTE CAPILAR COM EXTRAÇÃO DE UNIDADE FOLICULAR: CUIDADOS DIRECIONADOS AOS EVENTOS ESPERADOS E COMPLICAÇÕES PÓS-OPERATÓRIAS
Proper care and management are crucial for successful hair transplants and minimizing complications.
research Contraindications of Using Fractional CO2 Laser in the Treatment of Aesthetic Disorders: A Narrative Review
Careful patient selection is crucial for safe and effective fractional CO2 laser therapy.
research Autologous Mini Punch Graft in Vitiligo: A Narrative Review
Autologous mini-punch grafting can effectively repigment stable vitiligo, but has some risks and limitations.