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research Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene ID2, by contact sensitizers in human bulge‐derived keratinocytes

6 citations , January 2010 in “Journal of Biochemical and Molecular Toxicology”

The ID2 gene can help distinguish between sensitizers and irritants in skin cells.

research Tunable Keratin Hydrogels for Controlled Erosion and Growth Factor Delivery

106 citations , December 2015 in “Biomacromolecules”

Keratin hydrogels can be customized for better tissue healing.

research Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma

234 citations , September 2004 in “Clinical cancer research”

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

research Hard Keratin IF and Associated Proteins

22 citations , January 1990

research Faculty Opinions recommendation of The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.

December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

The KDM1 gene helps Venus flytraps close by managing potassium ions.

research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles

34 citations , October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”

research Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling

1 citations , January 2025 in “Burns & Trauma”

Targeting Midkine can help reduce pain and itching in keloids.

research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity

15 citations , January 2014 in “Medicinal chemistry”

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit

9 citations , September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.

research The occurrence of the ε-(γ-glutamyl)lysine cross-link in the medulla of hair and quill

49 citations , January 1972 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

research Keratin-Associated Protein Nanoparticles as Hemostatic Agents

11 citations , November 2021 in “ACS applied nano materials”

Keratin-associated protein nanoparticles from human hair may help stop bleeding quickly and safely.

research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants

July 2025 in “Journal of Investigative Dermatology”

TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.

research Role of sgk1 in cancer: a bibliometric analysis from 2013 to 2023—review article

3 citations , November 2024 in “Egyptian Journal of Medical Human Genetics”

SGK1 is important in cancer growth and treatment resistance, and targeting it could improve therapies.

research Enzymatic Crosslinking of Amino Acids Improves the Repair Effect of Keratin on Hair Fibre

May 2023 in “Polymers”

Using enzymes to link proteins makes hair repair treatments more effective and long-lasting.

research Simultaneous Typing of Erythrocyte Acid Phosphatase, Adenylate Kinase and Adenosine Deaminase in Human Hair Root Sheaths

1 citations , September 1986 in “Journal of the Forensic Science Society”

Hair root sheaths can be used to accurately analyze genetic markers.

research Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression.

26 citations , January 2015 in “PubMed”

Collagenase IV helps control hair growth by affecting certain growth factors.

research Construction and Activity Analysis of K14/K5 Promoter Vector Containing Luciferase Gene

January 2011 in “Xibei nongye xuebao”

The K14 promoter is more active in skin cells than the K5 promoter.

High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase

5 citations , July 2014 in “Acta Crystallographica Section D-biological Crystallography”

Mutations in the enzyme don't significantly change how it binds to its specific substances.

research Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts

38 citations , January 2014 in “Journal of Dermatological Science”

Krtap11-1 is important for hair strength and structure.

research Skin Keratins

54 citations , November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology”

Keratins are important for skin cell health and their problems can cause diseases.

research Homo- and heteropolymer self-assembly of recombinant trichocytic keratins

13 citations , July 2017 in “Biopolymers”

Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.

research [An immunohistochemical study on the normal human skin using an anti-hair keratin monoclonal antibody (HKN-2)].

February 1985 in “PubMed”

research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases

1 citations , February 2024 in “Preprints.org”

Ginsenoside compound K shows promise for treating metabolic diseases like obesity and diabetes, but more research is needed on its safety and effectiveness.

research DiZyme: The Ultimate Resource for Nanozyme Multiple Catalytic Activity Prediction

1 citations , November 2023 in “Research Square (Research Square)”

DiZyme accurately predicts nanozyme activities to aid in discovering new applications.

research A hairy kinase

August 2005 in “The Journal of Cell Biology”

Sgk3 kinase is essential for normal hair growth in mice.

research Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice

9 citations , June 2017 in “Pharmacological Reports”

ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.

research Trans glutaminase-mediated cross-linking in mammalian epidermis

44 citations , January 1984 in “Molecular and Cellular Biochemistry”

research Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells

April 2025 in “Journal of the Association for Research in Otolaryngology”

NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.

research Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera.

66 citations , April 1995 in “The journal of cell biology/The Journal of cell biology”

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

research Keratinocyte Cytokine Networks Associated with Human Melanocytic Nevus Development

5 citations , September 2018 in “Journal of Investigative Dermatology”

Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.

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