May 2021 in “American journal of medical sciences and medicine” Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.
1425 citations
,
September 2020 in “Open Biology” Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
1036 citations
,
August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
710 citations
,
May 2023 in “European Urology” Prostate cancer is common, but risk can be reduced by avoiding smoking, unhealthy diet, inactivity, certain medications, and risky jobs.
400 citations
,
January 2014 in “British Journal of Sports Medicine” The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.
346 citations
,
April 2020 in “Frontiers in Oncology” EMT and metabolic pathways help cancer cells resist treatment and spread.
318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
146 citations
,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
130 citations
,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
110 citations
,
September 2017 in “Molecules” Forsythiae Fructus has anti-inflammatory, antibacterial, and antiviral properties, with differences between unripe and ripe forms important for clinical use.
106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
83 citations
,
May 2022 in “Journal of Advanced Research” Enhancing glycolysis in mesenchymal stromal/stem cells boosts their immune functions and therapy potential.
79 citations
,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
76 citations
,
February 2007 in “Cancer Research” Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.
73 citations
,
August 2019 in “Cell Proliferation” Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.
67 citations
,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
59 citations
,
July 2023 in “PLoS ONE” Metabolic syndrome is common in African populations, needing urgent prevention and treatment.
55 citations
,
December 2021 in “BMC Veterinary Research” Certain genes in Iranian sheep are linked to wool production and heat adaptation.
50 citations
,
April 2021 in “Frontiers in Immunology” New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
48 citations
,
January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
45 citations
,
May 2022 in “Biomedicines” Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
42 citations
,
July 2017 in “Molecular therapy” A form of vitamin E promotes hair growth by activating a specific skin pathway.
40 citations
,
August 2021 in “International Journal of Molecular Sciences” The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
37 citations
,
April 2021 in “Nutrients” Berberine and curcumin may help reduce obesity by improving gut bacteria and liver health.
35 citations
,
July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
34 citations
,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
33 citations
,
March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
33 citations
,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.