research Classic versus non‐classic: A survival Kit for life in the skin
Melanocytes in different body areas have evolved to perform specific functions based on their location.
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research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity
The skin can independently form immune responses through special structures, offering new ways to treat skin diseases.
research Melanocytes in regenerative medicine applications and disease modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Editor's evaluation: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation
Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
research The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation
miR-21 helps improve ovarian function recovery in treated mice.
research The impact of VDR expression and regulation in vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research Role of the SOX family in cancer immune evasion: Emerging player and promising therapeutic opportunities
Targeting SOX proteins may improve cancer treatment by restoring immune function.
research Hair Follicle Stem Cell SLC3A2 Regulates Epithelial Regenerative Properties
SLC3A2 is crucial for hair follicle stem cell function and hair growth.
research PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats
PSAT1 is key for hair growth and stem cell function in cashmere goats.
research Immunomodulatory properties of mesenchymal stromal/stem cells: The link with metabolism
Enhancing glycolysis in mesenchymal stromal/stem cells boosts their immune functions and therapy potential.
research Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart
Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
research Making the head: Caspases in life and death
Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
research Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
A holistic approach is crucial for treating skin disorders and restoring barrier function.
research Impact of Vitamin D on Immunopathology of Hashimoto’s Thyroiditis: From Theory to Practice
Vitamin D may help reduce thyroid antibodies and improve thyroid function in Hashimoto's Thyroiditis.
research PolyQ length co-evolution in neural proteins
PolyQ repeats in neural proteins evolve together, affecting brain function and disease.
research Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
research Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Tissue fibrosis associated depletion of lipid‐filled cells
Fibrosis causes loss of important fat cells, affecting tissue function.
research Novel acquisitions on the immunoprotective roles of the EGF receptor in the skin
EGF receptor is crucial for skin health and its inhibitors can cause skin rashes.
research Revealing novel insights on how oral supplementation with collagen peptides may prevent hair loss: Lessons from the human hair follicle organ culture
Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
research Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice
Lack of vitamin D receptor increases skin tumor risk by boosting hedgehog signaling.
research Chitosan stimulates root hair callose deposition, endomembrane dynamics, and inhibits root hair growth
Chitosan affects root hair growth and callose deposition based on its concentration.
research Animal and in vitro Models for the Study of Hair Follicles
Understanding hair follicles through various models can help develop new treatments for hair disorders.
research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications
Polydopamine is promising for personalized medicine and biomedical technology due to its strong adhesion and biocompatibility.
research Plerixafor Biases CXCR4 Signaling Through β-Arrestin to Promote Melanogenesis via β-Catenin–MITF Activation
Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
research Prolactin as a candidate sebotrop(h)ic hormone?
Prolactin may influence skin glands and could be a target for treating acne and skin aging.