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research Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease

118 citations , April 2020 in “Stem Cell Research & Therapy”

IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.

research Stimulation of Hair Growth by Small Molecules that Activate Autophagy

88 citations , June 2019 in “Cell reports”

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

research Molecular mechanisms of asymmetric divisions in mammary stem cells

79 citations , November 2016 in “EMBO Reports”

Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.

research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats

75 citations , September 2007 in “Journal of Heredity”

FGF5 gene mutations cause long hair in domestic cats.

research Germline Mutation in ATR in Autosomal- Dominant Oropharyngeal Cancer Syndrome

71 citations , February 2012 in “The American Journal of Human Genetics”

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

research Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids

61 citations , April 2018 in “Frontiers in endocrinology”

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

60 citations , December 2020 in “Stem Cell Research & Therapy”

ASC-CM is more effective than EV for treating osteoarthritis.

research Signature selection analysis reveals candidate genes associated with production traits in Iranian sheep breeds

55 citations , December 2021 in “BMC Veterinary Research”

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

research Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome

53 citations , November 2021 in “Molecular Human Reproduction”

N-acetylcysteine may help treat uterine and placental issues in PCOS.

research LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

53 citations , April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

research Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone

53 citations , July 2014 in “American Journal of Physiology-Endocrinology and Metabolism”

Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.

research Immune-Epithelial Cross Talk in Regeneration and Repair

52 citations , January 2023 in “Annual Review of Immunology”

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

research Engineered extracellular vesicles for tissue repair and regeneration

51 citations , January 2024 in “Burns & Trauma”

Engineered extracellular vesicles can improve tissue repair and regeneration.

research Alarmin Cytokines as Central Regulators of Cutaneous Immunity

51 citations , March 2022 in “Frontiers in Immunology”

Alarmin cytokines are key in controlling skin immunity and inflammation.

research S100A6: molecular function and biomarker role

50 citations , September 2023 in “Biomarker Research”

S100A6 is important for cell functions and can help diagnose and treat diseases.

research Morphea: progress to date and the road ahead

50 citations , March 2021 in “Annals of Translational Medicine”

More research is needed to understand and treat morphea effectively.

research Nanobiotechnology: Applications in Chronic Wound Healing

48 citations , July 2022 in “International Journal of Nanomedicine”

Nanobiotechnology could improve chronic wound healing and reduce costs.

research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis

47 citations , September 2012 in “Human molecular genetics online/Human molecular genetics”

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

research Toll-like receptor-targeted anti-tumor therapies: Advances and challenges

44 citations , November 2022 in “Frontiers in Immunology”

TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.

research In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond

44 citations , September 2020 in “International Journal of Molecular Sciences”

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

research Progress in studies of epidermal stem cells and their application in skin tissue engineering

44 citations , July 2020 in “Stem Cell Research & Therapy”

Epidermal stem cells show promise for skin repair and regeneration.

research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling

43 citations , January 2016 in “Cellular physiology and biochemistry”

Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.

research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling

42 citations , July 2017 in “Molecular therapy”

A form of vitamin E promotes hair growth by activating a specific skin pathway.

research Inhibition of Wnt/β‐catenin pathway promotes regenerative repair of cutaneous and cartilage injury

41 citations , August 2015 in “The FASEB Journal”

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

research Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration

37 citations , February 2024 in “Military Medical Research”

Biomaterials can help heal wounds without scars and regenerate skin features.

research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells

37 citations , November 2017 in “Medical Sciences”

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

research Stem cells supporting other stem cells

34 citations , January 2013 in “Frontiers in genetics”

Stem cells can help other stem cells by producing supportive factors.

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