Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Patients with acne vulgaris have lower serum irisin levels.
September 2023 in “medRxiv (Cold Spring Harbor Laboratory)” Long-COVID has diverse, long-term health impacts, especially in young people.
January 2023 in “International Journal of Zoology and Animal Biology” Canine hypothyroidism can be linked to diabetes, requiring thorough testing for proper diagnosis.
February 2022 in “International Journal of Complementary & Alternative Medicine” Good hair and scalp health indicate good overall health.
December 2016 in “Journal of evolution of medical and dental sciences” Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.
191 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
81 citations
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November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
3 citations
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January 2015 in “Nasza Dermatologia Online” Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.
1 citations
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January 2010 in “Serbian Journal of Dermatology and Venereology” The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
50 citations
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November 2010 in “Otolaryngologic Clinics of North America” Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.
2 citations
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January 2019 in “Springer eBooks” The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.
Changes in skin bacteria can affect hair loss and new treatments targeting these bacteria may prevent balding without sexual side effects.
144 citations
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March 2013 in “Circulation Research” K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
85 citations
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July 2025 in “Nature Communications” Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
305 citations
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July 2016 in “International Journal of Biological Macromolecules” Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
207 citations
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April 2006 in “Journal of The American Academy of Dermatology” Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.
136 citations
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May 2016 in “Phytotherapy Research” Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.
134 citations
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January 2019 in “American journal of clinical dermatology” Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
125 citations
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May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
116 citations
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December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
95 citations
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April 2013 in “PLOS ONE” Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.
77 citations
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July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
76 citations
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December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
73 citations
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January 2013 in “European journal of dermatology/EJD. European journal of dermatology” Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
72 citations
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December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.