research Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis
Mycophenolate mofetil is safer and more effective than cyclophosphamide for treating lupus nephritis.
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510-540 / 1000+ resultsresearch Understanding the Role of Type I Interferons in Cutaneous Lupus and Dermatomyositis: Toward Better Therapeutics
A 29-year-old female with clinically amyopathic dermatomyositis presented with persistent cutaneous symptoms, including a pruritic rash, hair loss, and severe scalp pruritus, despite treatment with methotrexate and mycophenolate mofetil. This case underscores the challenges in managing skin manifestations in dermatomyositis and cutaneous lupus erythematosus (CLE), particularly the role of type I interferons (IFN) in the pathogenesis and treatment of these conditions. The study raises questions about the potential for IFN-targeted therapies to improve outcomes in patients with skin disease associated with CLE and DM.
research A Case Report of Thrombotic Thrombocytopenic Purpura Associated with Systemic Lupus Erythematosus: Overlapping Features
Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.
research The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Castleman’s Disease Combined with the Development of Systemic Lupus Erythematosus
A 16-year-old boy with Castleman's disease and lupus was successfully treated and showed no recurrence.
research Efficacy Observation on Mild to Moderate Active Systemic Lupus Erythematosus Treated with Compound Zishenqing Formula
The compound zishenqing formula is effective and safe for treating mild to moderate systemic lupus erythematosus.
research Case Report: Rare aplastic anemia in pediatric systemic lupus erythematosus: a case series and systematic literature review
Early detection and infection prevention are crucial for improving survival in pediatric lupus patients with aplastic anemia.
research Hereditary Chorea Associated With and Aggravated by Systemic Lupus Erythematosus
A girl with hereditary chorea, likely Huntington's disease, had her condition worsened by lupus.
research Favourable interactions of cytostatic and steroid drugs in treatment of systemic lupus erythematosus.
Combining cytostatic and steroid drugs effectively treats systemic lupus erythematosus.
research Hair loss and bronze discoloration of the skin in lupus erythematosus
research P44 An acutely unwell and rare presentation of systemic lupus erythematosus; a case report
Early recognition and treatment of SLE can improve outcomes in patients with complex symptoms.
research Referee report. For: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 1 approved, 1 approved with reservations, 1 not approved]
TB lymphadenitis can occur in people with weakened immune systems, like those with SLE.
research Referee report. For: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 1; peer review: 2 approved with reservations, 1 not approved]
TB lymphadenitis can occur in people with weakened immune systems, like those with SLE.
research Referee report. For: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]
People with weakened immune systems, like those with SLE, are at higher risk for TB.
research Referee report. For: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 1; peer review: 2 approved with reservations]
TB lymphadenitis can occur in people with weakened immune systems, like those with SLE.
research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1
A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.
research CLINICAL NUTRITION PROGRAM IMPROVES FATIGUE, ANXIETY, BRAIN FOG AND IMMUNO-HORMONAL AND GASTROINTESTINAL SYMPTOMS IN A 40 YEAR OLD FEMALE WITH SYSTEMIC ERYTHEMATOUS LUPUS
A nutrition program significantly improved a woman's lupus symptoms.
research Trichoscopic Signs in Dermatomyositis, Systemic Lupus Erythematosus, and Systemic Sclerosis: A Comparative Study of 150 Patients
Trichoscopy can help diagnose and assess disease activity in connective tissue diseases by identifying specific hair and scalp signs.
research Mesenchymal stem cells and their secretome - candidates for safe and effective therapy for systemic lupus erythematosus
Mesenchymal stem cells and their secretome may offer a safe and effective treatment for systemic lupus erythematosus.
research Alopecia areata-like patchy non-scarring alopecia as an initial presentation of systemic lupus erythematosus
research Case Report: Triple autoimmune overlap: rheumatoid arthritis, systemic lupus erythematosus, and hypereosinophilic asthma with systemic manifestations
This case report describes a 44-year-old woman with a rare triple autoimmune overlap of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and hypereosinophilic asthma with systemic manifestations (HASM). Initially managed as ANCA-negative eosinophilic granulomatosis with polyangiitis (EGPA), her condition was reclassified as HASM due to the absence of ANCA and biopsy-proven vasculitis. Treatment with high-dose glucocorticoids, methotrexate, and hydroxychloroquine led to rapid normalization of eosinophils and remission of asthma and sinus disease. The report highlights the importance of evaluating new-onset eosinophilic asthma in patients with rheumatic diseases for EGPA-spectrum or hypereosinophilic disorders, as timely EGPA-type immunosuppression can prevent organ damage.
research P47 Condition overlay and diagnostic delay – A challenging case of fibromyalgia and systemic lupus erythematosus
Timely diagnosis of SLE is crucial due to symptom overlap with fibromyalgia.
research E031 Retinal vasculitis with Libman-Sacks endocarditis as presenting features of a systemic lupus erythematosus with antiphospholipid antibody syndrome patient
A young woman with visual issues and other symptoms was diagnosed with lupus and antiphospholipid syndrome, and improved with treatment.
research AB0697 COMPARISON OF COVID-19 VACCINATION WITH INFLUENZA VACCINATION IN KOREAN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: PERCEPTION, ADVERSE EVENTS, AND FLARES FROM THE CIVIL STUDY
COVID-19 vaccines had more side effects and worse perception than flu vaccines in Korean lupus patients.
research HAIR TONIC ACTIVITY TEST OF THE LEAVES OF THE LAW OF THE LAW (SANSEVIERIA TRIFASCIATA PRAIN) ON HAIR GROWTH OF MALE RABBITS (LEPUS NIGRICOLLIS)
Mother-in-law's tongue leaf extract at 20% concentration significantly promotes hair growth in male rabbits.
research Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice
A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.
research Microanatomical Observations of Hair Characteristics of Red Fox (Vulpes vulpes), Golden Jackal (Canis aureus), and Gray Wolf (Canis lupus): A Comparative Study
Red fox, golden jackal, and gray wolf hairs have similar features but differ in length, thickness, and inner structure.
research A systematic review of procedural modalities in the treatment of lichen planopilaris, frontal fibrosing alopecia, and discoid lupus erythematosus
research Dermatoses of pregnancy
Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
research Histopathology of non-scarring alopecia
The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.