research Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control
Functionalized hydrogels can help heal tissues and fight infections by delivering beneficial bacteria and antimicrobials.
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90-120 / 1000+ resultsresearch Comprehensive single-cell transcriptomic profiling of the scalp from patients with moderate-to-severe alopecia areata
Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
research Spatiotemporal immunomodulation by engineered hair follicle stem cell-derived nanovesicles enables scarless regeneration of infected wounds
Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
research Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection
The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
research Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Alarmin cytokines are key in controlling skin immunity and inflammation.
research CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing
Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
research Weathering the Storm: Harnessing the Resolution of Inflammation to Limit COVID-19 Pathogenesis
Reprogramming macrophages to resolve inflammation can help reduce severe COVID-19 complications.
research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
research Fibroblasts and wound healing: an update
Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
research Hematopoietic Stem Cells: Nature and Niche Nurture
Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Advances in genetic and molecular understanding of Omenn syndrome - implications for the future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research Research progress of post-acute sequelae after SARS-CoV-2 infection
Long COVID causes various long-term health issues and needs better awareness and treatment.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
research Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential
Wharton's jelly secretomes are best for promoting blood vessel growth.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Regulatory T cells in skin
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Impeding Glial Scarring Hyperplasia and Activating Axon Neogenesis via Immunomodulatory Microneedle Patch for Spinal Cord Repair
A new microneedle patch helps repair spinal cord injuries by reducing scarring and promoting nerve growth.
research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research Association of Alopecia Areata with Vitamin D and Calcium Levels: A Systematic Review and Meta-analysis
People with Alopecia Areata often have lower vitamin D levels, and vitamin D supplements might help treat it.
research The Application Progress of Tumor Microenvironment-Responsive Drug Carriers in Precision Chemotherapy
Tumor-targeted drug carriers can improve chemotherapy precision and reduce side effects.
research Skin melanocytes: biology and development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis
HT-scCAT-seq helps understand gene regulation in embryonic skin development.
research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Mechanotransduction unifies healthy non-diabetic wound healing over time by promoting a Cd14+/C1qa+ fibroblast subpopulation
Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
research Sculpting with stiffness: rigidity as a regulator of morphogenesis
Tissue stiffness helps shape how organisms develop.
research Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation
Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.