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,
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,
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176 citations
,
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,
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,
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,
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,
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68 citations
,
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54 citations
,
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49 citations
,
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47 citations
,
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44 citations
,
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40 citations
,
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38 citations
,
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28 citations
,
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28 citations
,
September 2011 in “Stem Cell Reviews and Reports” 24 citations
,
March 2024 in “Small Science” Single-cell encapsulation shows promise for medical use but faces production challenges.
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,
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23 citations
,
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23 citations
,
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21 citations
,
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19 citations
,
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19 citations
,
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18 citations
,
January 2018 in “BMC dermatology” A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.
17 citations
,
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16 citations
,
March 2024 in “International Journal of Molecular Sciences” Natural compounds and biomimetic engineering can improve wound healing by enhancing fibroblast activity.
15 citations
,
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,
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,
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14 citations
,
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