research The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
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research Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing
Angio PRP speeds up skin wound healing and reduces inflammation.
research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Notch1 Signaling Regulates Wound Healing via Changing the Characteristics of Epidermal Stem Cells
Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
research Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling
Sonic hedgehog signaling helps heal pressure ulcers by improving blood vessel growth.
research Evaluation of Gene Expression Patterns in Micrografts Demonstrate Induction of Catagen-Like Processes During Storage
Storing hair follicle micrografts for longer times can cause them to enter a state similar to the natural hair shedding phase, which might impact hair transplant results.
research A guide for building biological pathways along with two case studies: hair and breast development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?
Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
research Platelet-Rich Plasma for Hair Loss
Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
research Topical treatment with the bacterium-derived c-Met agonist InlB321/15 accelerates healing in the abrasion wound mouse model
Applying InlB321/15 to wounds sped up healing in mice.
research Pathophysiology of the burn scar
Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
research Atrichia with papular lesions in a Taiwanese patient without hairless (HR) gene mutation
A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
research Stem cells tightly regulate dead cell clearance to maintain tissue fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research Sodium alginate cross-linked hydroxypropyl methylcellulose/hydroxyapatite nano biomaterial mediated with zinc to promote bone tissue healing
The zinc-doped nanocomposite helps heal bone tissue effectively.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research Co-opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research M5 isolation method preserves higher trichogenic identity and proliferative capacity of human dermal papilla cells
The M5 method is best for isolating cells that help hair growth.
research PVA/Agar based films reinforced with pickering emulsion of Achillea millefolium L. essential oil
PVA/agar films with Achillea millefolium essential oil are promising for wound dressings due to good strength and selective antibacterial effects.
research Skin aging: mechanisms, evaluation, and rejuvenation
Skin aging can be slowed by targeting cells, hormones, and the microbiome.
research Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance
Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
research The orchestrated network of skin photoaging: From intercellular crosstalk to molecular signaling
UV radiation causes skin aging by damaging cells and triggering harmful processes.
research Immunomodulatory roles of regulatory T cells in cutaneous wound healing: mechanisms and therapeutic opportunities
Regulatory T cells help heal skin wounds by reducing inflammation and promoting tissue repair.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
research Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure
Lack of certain cells causes abnormal nipple development and nursing failure.
research The multifaceted regulatory effect of icariin on macrophages: a mini-review
Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.