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GlossaryMesenchymal Stem Cells

cells that can become bone, cartilage, or fat cells

Mesenchymal Stem Cells (MSCs) are a type of multipotent stem cell found in various tissues, including bone marrow, fat, and umbilical cord tissue. They have the ability to differentiate into a variety of cell types, such as bone, cartilage, and fat cells, making them valuable for regenerative medicine and tissue engineering.

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research Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation

7 citations , January 2022 in “Biomedicines”

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

research Development of a simple selection protocol for optimizing the harvest of mesenchymal stem cells from explanted human umbilical cord Wharton’s jelly

3 citations , June 2019 in “Asian Journal of Medical Sciences”

A new method improves stem cell harvest from umbilical cords, reducing time and cost.

research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model

13 citations , January 2022 in “Stem cell reviews and reports”

Mouse stem cells from hair follicles can improve wound healing and reduce scarring.

research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

773 citations , August 2017 in “International Journal of Molecular Sciences”

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Preclinical Efficacy and Safety Evaluation of a Topical Mesenchymal Stem Cell Derived Conditioned Media Gel for Oral Mucositis Management

research Preclinical efficacy and safety evaluation of a topical mesenchymal stem cell derived conditioned media gel for oral mucositis management

February 2026 in “Scientific Reports”

The gel is safe and effective for treating oral mucositis from chemotherapy and radiation.

research THE EFFECT OF HAIR TONIC FROM SECRETOME MESENCHYMAL STEM CELL ON HAIR GROWTH IN HAIR LOSS CASES

January 2026 in “International Journal of Applied Pharmaceutics”

A 10% MSC secretome hair tonic best promotes hair growth in alopecia.

research Autoimmunity and clinical pathology amelioration in SLE by Dexamethasone primed Mesenchymal Stem Cell derived conditioned media

July 2024

Dexamethasone-primed stem cell media shows promise in treating lupus by reducing symptoms and inflammation.

research Mesenchymal stem cell-derived protein extract induces periodontal regeneration

April 2024 in “Research Square (Research Square)”

MSC-protein helps regenerate gum tissue and bone.

research Regenerative potential and clinical application of mesenchymal stem cell-derived exosomes (review)

November 2023 in “Klìtinna ta organna transplantologìâ”

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia

research Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia

March 2026 in “Molecular and Cellular Biomedical Sciences”

EH-MSCs may help treat hair loss by reducing inflammation.

research Conditioned media derived from mesenchymal stem cell cultures: The next generation for regenerative medicine

88 citations , January 2019 in “Journal of Tissue Engineering and Regenerative Medicine”

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

research Efficacy of Placental-Derived Mesenchymal Stem Cell Exosome Therapy in Treating Androgenetic Alopecia: A Clinical Trial Study

December 2024 in “Research Square (Research Square)”

Placental stem cell exosome therapy improves hair growth and reduces hair loss.

Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

136 citations , May 2019 in “Cells”

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The Anti-Aging Effects of Adipose-Derived Mesenchymal Stem Cell Exosomes on Skin and Their Potential for Personalized Skincare Applications

research The Anti-Aging Effects of Adipose-Derived Mesenchymal Stem Cell Exosomes on Skin and Their Potential for Personalized Skincare Applications

1 citations , September 2025 in “Clinical Cosmetic and Investigational Dermatology”

Adipose-derived stem cell exosomes and AI can improve personalized skincare by offering anti-aging benefits and precise product customization.

Adipose-Derived Stem Cell Exosomes Promote Critical-Sized Bone Defect Repair by Enhancing the Homing of Bone Marrow Mesenchymal Stem Cells

research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells

January 2026

Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.

research Exploring the dermatological applications of human mesenchymal stem cell secretome: a comprehensive review

9 citations , April 2025 in “Stem Cell Research & Therapy”

MSC-derived conditioned media can improve skin treatments.

research Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application

53 citations , September 2020 in “Stem Cell Research & Therapy”

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

research Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis

3 citations , February 2025 in “Frontiers in Cell and Developmental Biology”

Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.

Morphometric Prediction of Mesenchymal Stromal Cell-Like Immunosuppressive Capacity of Human Hair Follicle Dermal Sheath Cup Cells: An Implication for Regenerative Medicine in Hair Loss Diseases

research Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases

November 2025 in “Stem Cell Research & Therapy”

Human hair follicle cells can help regenerate hair and reduce inflammation, aiding in hair loss treatment.

research Mesenchymal stem cell therapy for liver disease: full of chances and challenges

95 citations , October 2020 in “Cell & Bioscience”

Mesenchymal stem cell therapy shows promise for liver disease but faces challenges in standardization and approval.

research Efficacy assessment of mesenchymal stem cell transplantation for burn wounds in animals: a systematic review

21 citations , August 2020 in “Stem Cell Research & Therapy”

Stem cell therapy helps heal burn wounds faster in animals.

research A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model

February 2026

A stem cell-derived matrix speeds up healing of diabetic skin wounds.

research Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia

March 2025 in “World Journal of Stem Cells”

Stem cell exosomes may help treat hair loss by promoting hair growth.

research Modern aspects of external application and prospects of using the secretome of mesenchymal stem cells (review)

March 2024 in “Drug development & registration”

Mesenchymal stem cell secretome shows promise for skin treatments but needs more human trials.

Towards a Consensus Potency Assay for Mesenchymal Stromal Cells: A Matrix Analysis of Cell Source, Donor Variability, and Inflammatory Stimuli to Refine Surrogate Markers of Immunomodulation

research Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation

3 citations , May 2019 in “Cytotherapy”

ATIR101 improves survival in stem cell transplant patients; Australian stem cell treatment decisions are influenced by regulation changes.

research Advances In Mesenchymal Cell Therapy In Dermatology And Aesthetic Medicine

July 2024 in “Journal Of Stem Cell Research”

Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.

research Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro

116 citations , April 2020 in “Stem Cell Research & Therapy”

Wharton's jelly stem cells show diverse traits and functions.

research Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse model

9 citations , May 2023 in “Stem Cell Research & Therapy”

Stem cell treatment from umbilical cords reduces symptoms of atopic dermatitis and may help hair growth.

research Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints

8 citations , October 2021 in “Stem Cell Research & Therapy”

Mesenchymal stem cells may effectively treat and prevent allergic skin conditions.

Equine Hoof Stem Progenitor Cells (HPC) CD29+/Nestin+/K15+ – A Novel Dermal/Epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment

research Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + – a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment

6 citations , May 2021 in “Stem Cell Reviews and Reports”

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.