research The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
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research Challenges in treatment of patients with non-classic congenital adrenal hyperplasia
Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
research Progress of ursolic acid on the regulation of macrophage: summary and prospect
Ursolic acid may help develop new anti-inflammatory drugs by affecting immune cells.
research Prevalence of Cobalt in the Environment and Its Role in Biological Processes
Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
research Anti-Aging Potential of Platelet Rich Plasma (PRP): Evidence from Osteoarthritis (OA) and Applications in Senescence and Inflammaging
PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.
research Translating Resveratrol Research: A Systematic Review on Patents and Clinical Trials (2000–2025)
Resveratrol shows health benefits but faces challenges in effectiveness and regulation.
research Current Biomedical Applications of 3D-Printed Hydrogels
3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.
research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
research Tissue fibrosis associated depletion of lipid‐filled cells
Fibrosis causes loss of important fat cells, affecting tissue function.
research Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
research Pharmacological Activity of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Generation of functionally active resident macrophages from adipose tissue by 3D cultures
3D cultures can create active macrophages from fat tissue.
research Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
research Essential Oils and Melatonin as Functional Ingredients in Dogs
Essential oils may improve dogs' health and melatonin can help with their sleep and anxiety, but both should be used carefully.
research Vitamin D and the Skin: An Update for Dermatologists
Adequate vitamin D is crucial for skin health and should be considered in dermatology.
research Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering
Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
research Organ Specificity in Autoimmune Diseases: Thyroid and Islet Autoimmunity in Alopecia Areata
Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.
research Thyroid diseases and skin autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Man made disease: Clinical manifestations of low phenylalanine levels in an inadequately treated phenylketonuria patient and mouse study
Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.
research Male fertility and skin diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Bone Mineral Density is Unaltered in Women with Polycystic Ovary Syndrome
Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
research Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
Women with PCOS should be screened for heart disease risk and manage their health to prevent it.
research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Hair Amino Acids: Normal Values and Results in Metabolic Errors
Hair amino acid levels can indicate metabolic disorders.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research High-content drug screening for rare diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone
Testosterone therapy increases bone density in older men with low testosterone levels.
research 9 Role of 5α-reductase in health and disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.
research Transmasculine Hormone Therapy
Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.