47 citations
,
September 1997 in “Journal of Pharmaceutical Sciences” Properly formulated large molecules can reach active levels at the hair bulb.
128 citations
,
March 2016 in “Advanced Pharmaceutical Bulletin” Smaller nanoparticles penetrate skin better, especially through hair follicles.
March 2024 in “International journal of nanomedicine” Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
60 citations
,
October 2020 in “Journal of Controlled Release” Curcumin nanocrystals in simple gels effectively penetrate hair follicles, but humectants can reduce this efficacy.
September 2022 in “Journal of Plastic and Reconstructive Surgery” The article suggests that updating injection depth standards could improve the results of facial rejuvenation treatments.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” New nanocarriers were developed for safer, targeted drug delivery and diagnostics, showing promise for future medical use.
268 citations
,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
February 2026 in “Journal of Cosmetic Dermatology” Polynucleotide injections improved eye wrinkles with few side effects.
April 2023 in “Journal of Drug Delivery Science and Technology” The new minoxidil gel improves hair growth and reduces skin irritation.
14 citations
,
May 2005 in “Farmaco” A method was created in 2005 to identify minoxidil, a hair growth ingredient, in products using two types of capillary zone electrophoresis, and it found that most products had about 2% minoxidil.
47 citations
,
November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” PRP with microneedling is generally safe but can cause minor side effects like scalp itching, temporary hair shedding, and swollen lymph nodes.
January 2018 in “Sohag Medical Journal” Combining topical dutasteride with microneedling is more effective for hair growth than microneedling alone.
6 citations
,
July 2005 in “Farmaco” A quick and simple method was created to identify minoxidil in hair-growth products using micellar electrokinetic capillary chromatography.
January 2025 in “International Journal of Pharmaceutical Research and Applications” Hibiscus mucilage is an effective gelling agent for diclofenac diethylamine gel.
67 citations
,
February 2022 in “International Journal of Molecular Sciences” The nanofiber membranes effectively promote wound healing and have strong antibacterial properties.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
3 citations
,
April 2011 in “Expert Review of Dermatology” Mesotherapy lacks strong evidence for effectiveness and safety, and its ingredients are not FDA-approved for subcutaneous use.
132 citations
,
April 2007 in “European journal of pharmaceutics and biopharmaceutics” The microemulsion delivered the dye deeper into the skin than the cream.
Microneedling may improve neck scars, but more research is needed.
Liposomes with minoxidil and PEP penetrate skin slowly but reach deeper layers than foam.
1 citations
,
January 2024 in “BioMed research international”
August 2022 in “Yakugaku zasshi” Using a steam towel, l-menthol, and carpronium before applying minoxidil nanoparticles can increase its absorption and potentially improve hair growth.
59 citations
,
July 2015 in “Journal of innovative optical health sciences/Journal of innovation in optical health science” Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
March 2023 in “Clinical Cosmetic and Investigational Dermatology” Microneedling and fractional CO2 laser are compared as methods for delivering stem cell secretomes for skin rejuvenation.
7 citations
,
February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
14 citations
,
November 2021 in “Nanoscale” The research shows how a specially structured nanoemulsion delivers vitamins A and E through the skin.
1 citations
,
December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
2 citations
,
January 2012 in “Hair therapy & transplantation” DDAIP-HCl significantly increases minoxidil absorption into the skin.
1 citations
,
July 2021 in “Current nanomedicine” The new gel formulation for Acitretin improves topical delivery and reduces oral toxicity.