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GlossaryMicrovessel Density

number of tiny blood vessels in a specific tissue area

Microvessel Density (MVD) refers to the number of tiny blood vessels, or microvessels, within a specific area of tissue. It is often used as a measure in medical research to assess the extent of angiogenesis, which is the formation of new blood vessels, particularly in the context of tumor growth and other pathological conditions. High MVD can indicate increased blood supply to a tumor, which may correlate with more aggressive disease and poorer prognosis.

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The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

90 citations , January 2003 in “The Journal of Urology”

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

research Expression and localization of the vascular endothelial growth factor and changes of microvessel density during hair follicle development of Liaoning cashmere goats

4 citations , January 2013 in “Genetics and Molecular Research”

VEGF and microvessel density are closely linked and peak during specific hair growth phases in cashmere goats.

research Study on VEGF in the Expression of Skin Hair Follicle and the Relationship with Microvessel Density by Liaoning Cashmere Goat in Fetal Period

1 citations , January 2013 in “China Animal Husbandry & Veterinary Medicine”

VEGF increases in goat hair follicles during fetal development, boosting skin blood vessel density.

Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density

research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Micro Vessel Density

January 2024

Recombinant human growth hormone helps burn wounds heal faster by increasing blood vessel growth.

research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats

7 citations , March 2015 in “The American Journal of the Medical Sciences”

Finasteride helps reduce blood vessel growth in diabetic rat kidneys.

Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute

45 citations , October 2014 in “Stem cell research & therapy”

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors

41 citations , July 2016 in “Radiation Research”

Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.

research Radiofrequency treatment induces fibroblast growth factor 2 expression and subsequently promotes neocollagenesis and neoangiogenesis in the skin tissue

32 citations , May 2017 in “Lasers in medical science”

Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.

research Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells

13 citations , September 2014 in “BMC Complementary and Alternative Medicine”

Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.

research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats

12 citations , February 2023 in “Stem Cell Research & Therapy”

HGF-modified hair follicle stem cells help brain recovery after injury in rats.

research Effect of a portable light emitting diode device on wound healing in a rat model

5 citations , October 2023 in “International Wound Journal”

The portable LED device speeds up wound healing.

research Should Finasteride Be Routinely Given Preoperatively for TURP?

2 citations , July 2013 in “ISRN Urology (Print)”

Finasteride may reduce bleeding after TURP, but more research needed.

Tendon Decellularized Extracellular Matrix Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing

research Tendon dECM Composited with Chitosan with Loading Skin Precursor Stem Cell Exosome for Enhanced Diabetic Wound Healing

April 2026 in “Gels”

The hydrogel treatment speeds up healing of diabetic wounds.

research Hair follicle transplantation promotes skin ulcer healing in a mouse model of experimental diabetes

August 2025 in “Scientific Reports”

Hair follicle transplantation speeds up wound healing in diabetic mice.

research “How can stem cells improve the function of skin grafts”

January 2025

Stem cells can improve skin grafts by enhancing blood flow and hair growth.

research Vascularization of skin substitute constructed by vascular endothelial growth factor 165 gene-modified hair follicle stem cells compounded with three-dimensional gelatin-chondroitin sulfate-hyaluronic acid

June 2014

The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.

research Finasteride given pre-operation on decreasing bleeding during TURP and its possible mechanisms: a Meta-analysis

January 2011 in “Shandong yiyao”

Finasteride reduces bleeding during prostate surgery.

research Effects of Yiqi Huayu Chinese Medicine on the Expression of MMP-2/TIMP-2 in BPH Rats

January 2011 in “Zhonghua zhongyiyao xuekan”

Yiqi Huayu medicine can effectively reduce BPH in rats by lowering MMP-2 levels and blood vessel growth.

research A new model of blood vessel remodeling

January 2002

Hair follicles influence blood vessels during hair growth, suggesting potential treatments for hair growth issues.

Retraction of: Transurethral Resection of Prostate and Bleeding: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial to See the Efficacy of Short-Term Use of Finasteride and Dutasteride on Operative Blood Loss and Prostatic Microvessel Density

research Retraction of: Bansal and Arora. J Endourol. Epub ahead of print; DOI: 10.1089/end.2016.0696

March 2017 in “Journal of endourology”

The journal retracted an article due to inaccurate statistics and asked the authors to revise and resubmit it.

research [Finasteride inhibits microvascular density and VEGF expression in the seminal vesicle of rats].

May 2018 in “PubMed”

Finasteride reduces blood vessel formation in seminal vesicles.

research Short-term cryoprotectant-free cryopreservation at −20°C does not affect the viability and regenerative capacity of nanofat

July 2024 in “Frontiers in Bioengineering and Biotechnology”

Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.

research Effects of Finasteride on Vascular Endothelial Growth Factor

35 citations , January 2002 in “Scandinavian Journal of Urology and Nephrology”

Finasteride reduces prostate bleeding by affecting blood vessel growth.

research Dracorhodin Perchlorate Regulates the Expression of Inflammatory Cytokines through the TLR4 Pathway and Improves Skin Wound Healing in Diabetic Rats

4 citations , April 2022 in “Evidence-based Complementary and Alternative Medicine”

Dracorhodin perchlorate helps heal wounds in diabetic rats by reducing inflammation.

The Potential of Circulating Endothelial Cells as Prognostic Biomarkers in Prostate Cancer

research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives

4 citations , September 2021 in “Biomolecules”

Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.