488 citations
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July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
387 citations
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May 2019 in “International Journal of Molecular Sciences” Adipose-derived stem cells are promising for regenerative medicine due to their accessibility, versatility, and low risk of immune rejection.
346 citations
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April 2020 in “Frontiers in Oncology” EMT and metabolic pathways help cancer cells resist treatment and spread.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
317 citations
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April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
294 citations
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January 2016 in “Stem Cells International” Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
286 citations
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August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
277 citations
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December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
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October 2017 in “International Journal of Molecular Sciences” Improving mesenchymal stromal cell therapies requires overcoming cell death and optimizing delivery methods.
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February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
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December 2007 in “Journal of Investigative Dermatology” Hair follicles prevent NK cell attacks to avoid hair loss.
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April 2009 in “Journal of Biological Chemistry” p2y5, now called LPA6, is a receptor important for human hair growth.
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February 2022 in “Nanomaterials” Electrospun gelatin-based nanofiber dressings are promising for wound healing due to their effective healing properties and ability to protect against infections.
200 citations
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March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
192 citations
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January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
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December 2020 in “Foods” Polyphenols in plant foods help prevent diseases and have potential uses in food, cosmetics, and more.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
153 citations
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June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
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August 2022 in “Stem Cell Research & Therapy” Encapsulated stem cell exosomes in hydrogel improve wound healing.
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May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
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April 2021 in “Stem Cell Research & Therapy” A special membrane with cell particles helps heal diabetic wounds faster.
130 citations
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December 2022 in “Antioxidants” Natural polysaccharides have strong antioxidant properties that help fight diseases like Alzheimer's, diabetes, and heart disease.
126 citations
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August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
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November 2019 in “International Journal of Molecular Sciences” Standardized kits improve the quality and consistency of isolating stem cells from fat tissue.
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
113 citations
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July 2020 in “International Journal of Molecular Sciences” Allogenic ASCs and ECM transplants are safe and effective for tissue regeneration.
112 citations
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September 2021 in “BMC Biology” Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.
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April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.