88 citations
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January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
87 citations
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March 2020 in “Australian Dental Journal” Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
76 citations
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December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
76 citations
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June 2015 in “Journal of biomedical science” Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
75 citations
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June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
73 citations
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September 2016 in “Journal of Translational Medicine” Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
71 citations
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September 2007 in “Cancer” Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
70 citations
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
70 citations
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July 2016 in “Aging” Targeting dermal adipocytes may help combat skin aging.
68 citations
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June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
67 citations
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November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
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January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
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December 2013 in “PLoS ONE” Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
60 citations
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May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
60 citations
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November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
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June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
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January 2021 in “Clinical and Experimental Medicine” The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
53 citations
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September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
52 citations
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September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
51 citations
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January 2024 in “Burns & Trauma” Engineered extracellular vesicles can improve tissue repair and regeneration.
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January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
48 citations
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
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September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
45 citations
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January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
45 citations
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February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” *Acorus calamus* has many medicinal benefits but needs more safety research.
43 citations
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January 2016 in “Oxidative medicine and cellular longevity” THSG from a Chinese plant helps with aging and related diseases.
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November 2024 in “Molecular Biomedicine” Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
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December 2019 in “Stem Cell Reviews and Reports” Tooth regeneration could become possible by controlling how and when bioactive factors are released.