47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
13 citations
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April 2009 in “Acta Medica Scandinavica” Minoxidil lowers blood pressure and causes hair growth, with some side effects.
3 citations
,
February 2017 in “The American journal of medicine” A woman's heart failure improved after she added vitamins and changed her diet from only cheese chips and cake.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.
19 citations
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January 1993 in “Dermatologic Clinics”
31 citations
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August 1975 in “Journal of Pharmaceutical Sciences” Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
22 citations
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February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
January 2021 in “ABC Heart Failure & Cardiomyopathy” When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.
119 citations
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June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
June 1982 in “Reactions (Auckland)” Metoprolol and propranolol may cause hair loss.
November 1999 in “Reactions Weekly”
1 citations
,
October 2023 in “Journal of clinical psychopharmacology” Divalproex sodium can cause pleural effusion, which stops when the drug is discontinued.
1 citations
,
March 2014 in “Senses and Sciences” A supplement with Serenoa repens improved hair loss in a patient.
137 citations
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October 2009 in “The American journal of pathology” Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
35 citations
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August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
June 2016 in “Makedonski medicinski pregled” A man who drank too much hair growth medication got very sick but got better after hospital treatment.
January 2026 in “New Journal of Chemistry” Minoxidil-loaded nanoparticles improve hair loss treatment by enhancing delivery and reducing irritation.
54 citations
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May 1977 in “The Journal of Pediatrics” Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
7 citations
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August 2025 in “European Journal of Endocrinology” Long-term use of calcineurin inhibitors in transplant patients can cause hormone issues that can be managed with proper care.
3 citations
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April 2009 in “Congestive Heart Failure” Sympathetic activation and venous tone are crucial for heart failure symptoms.
3 citations
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July 2005 in “DOAJ (DOAJ: Directory of Open Access Journals)” Selenosis in calves causes health issues and changes in blood parameters.
9 citations
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March 1968 in “The BMJ” A woman's severe skin reaction was caused by an allergy to a skin treatment.
11 citations
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March 2007 in “Journal of Hypertension” Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.
January 2023 in “Open veterinary journal” A cat developed skin problems from a certain brand of injected water pills, which went away after switching brands.
July 2024 in “Journal of Investigative Dermatology” A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.
July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.
1 citations
,
April 2006 in “International Journal of Oncology” Lysocellin helps stop cell damage from etoposide and may prevent hair loss.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” Minoxidil protects brain tissue directly, not by lowering blood pressure.
53 citations
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January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
245 citations
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January 2010 in “Blood” Antihepcidin antibodies may treat inflammation-induced anemia by improving iron metabolism.