13 citations
,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
10 citations
,
April 2008 in “Journal of Pediatric Surgery” P-selectin is not the only factor that prevents scarring in fetal wound healing in mice.
9 citations
,
February 2019 in “BMC cancer” M30 is a promising treatment for preventing hair loss during chemotherapy.
8 citations
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June 2024 in “APOPTOSIS” Caspases affect many cell functions and could help treat various diseases.
7 citations
,
June 2016 in “Bone Research” A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
3 citations
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February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY” Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
2 citations
,
September 2020 in “Schweizer Archiv für Tierheilkunde” Swiss Holstein cattle with curly, short hair carry genes from the Simmental breed.
2 citations
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May 2018 in “Expert opinion on orphan drugs” Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
1 citations
,
August 2024 in “Transgenic Research” Activated β-catenin affects hair growth and skin thickness, and changes are reversible.
December 2024 in “Frontiers in Veterinary Science” Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.
January 2021 in “Medical Research Archives” Genetically modified rats help reveal how vitamin D affects bone and skin health.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
January 2016 in “SpringerBriefs in bioengineering” Genetic defects and UV radiation cause skin damage and aging.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
116 citations
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September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
111 citations
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March 1951 in “Annals of the New York Academy of Sciences” Understanding the mouse hair cycle is crucial for cancer research.
103 citations
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October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
77 citations
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February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
23 citations
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January 2009 in “Veterinary Dermatology” The hepatitis B vaccine did not cause hair loss in the tested mice.
19 citations
,
June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
19 citations
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November 1993 in “Mammalian Genome” A gene mutation in mice causes permanent hair loss and skin issues.
15 citations
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June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
7 citations
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April 2013 in “Journal of Cellular Biochemistry” CD61 is important for mouse tooth cell growth and works through Lgr5.
4 citations
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February 2025 in “BMC Genomics” Black wool in Qira sheep is linked to specific gene mutations, especially in the TYRP1 gene.
2 citations
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August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
2 citations
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December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.
2 citations
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August 2020 in “Natural Product Communications” A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.
2 citations
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October 2010 in “Journal of dermatological treatment” External treatments can change hair growth patterns in nude mice.
1 citations
,
November 2017 in “Expert opinion on orphan drugs” Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.