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Older Julia Creek dunnarts often have reproductive and hormonal health issues.

Dermal lymphatic vessels help hair growth by affecting hair cycle phases.

TSC2 is crucial for proper hair follicle development and patterning.

Zfp157 is active in many mouse tissues during development and in specific adult cells.

Major histocompatibility antigens are found in specific skin cells and structures, but not in sweat glands.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

Follicular mucinosis in a 15-year-old is usually harmless but needs monitoring for possible lymphoma.

Meibomian glands are highly specialized and differ significantly from other sebaceous glands in structure and function.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Wnt ligand secretion by hair follicle cells is essential for hair growth and repair.

Estradiol stops hair growth in mice, but an antagonist can reverse this effect.

Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.

Hairless USP mice have enlarged skin cysts as they age.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Higher thyroid hormone levels may be linked to certain types of polycystic ovary syndrome.

Machine learning can accurately diagnose PCOS non-invasively using clinical and ultrasound features.

Obese and lean women with PCOS have different symptoms and need different treatments.

Women with different PCOS types have similar fertility treatment results.

PCOS is a common hormonal disorder in women that can lead to serious health problems.

Benign ovarian tumors can cause excess male hormones and related conditions in postmenopausal women.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

A woman's severe hirsutism was caused by Leydig cell tumors in her ovaries, which improved after surgery.