April 2019 in “Molecular Informatics” Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
June 2024 in “Ecotoxicology and Environmental Safety” Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
January 2008 in “US endocrinology” Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
21 citations
,
January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
18 citations
,
October 1978 in “The journal of investigative dermatology/Journal of investigative dermatology” Excess vitamin A causes lasting gland changes in mouse hair follicles.
SLC24A5 shows a clear selective sweep, but no link to UV radiation intensity.
November 2025 in “Journal of Investigative Dermatology” A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.
1 citations
,
July 1988 in “JAMA” Metronidazole can cause lung disease.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
May 2024 in “International journal of medicine and psychology.” Age-related immune changes significantly affect disease development in other systems.
26 citations
,
February 2015 in “Pediatric blood & cancer” Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
403 citations
,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
January 2025 in “Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
1 citations
,
October 2025 in “Scientific Reports” Sonidegib and vismodegib have different side effects and reporting patterns.
47 citations
,
April 2012 in “Analytical and Bioanalytical Chemistry” The mutation helps mice handle heat better without affecting hair growth.
January 2020 in “Figshare” Finasteride worsens heart damage but reduces cell toxicity caused by nandrolone decanoate.
10 citations
,
February 2022 in “Cancers” More research and guidelines are needed for managing prostate cancer in people with high-risk genetic mutations.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
September 2017 in “Journal of Investigative Dermatology” Mackerel fermented fish oil protects skin cells from damage by UVB light.
15 citations
,
June 2021 in “Journal of Genetic Engineering and Biotechnology” Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
September 2025 in “Cosmetics” Genetic profiling can improve androgenetic alopecia treatment by predicting drug response and minimizing side effects.
2 citations
,
February 2023 in “Transgenic Research” The E2 protein affects gene activity in hair follicles of mice.
March 2024 in “Organic letters” A new method efficiently modifies alkenes to create useful medicinal compounds.
172 citations
,
July 2007 in “Journal of Dermatological Science” Stat3 helps skin heal but can also cause skin diseases if overactive.
6 citations
,
April 2019 in “Pesquisa Veterinária Brasileira” Milk can carry harmful plant toxins that pose health risks to animals and humans.
45 citations
,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
15 citations
,
August 2008 in “Toxicology Letters” High doses of minoxidil can harm marmoset hearts and kidneys, possibly affecting humans similarly.
July 2025 in “Reproductive Biology” Finasteride use in male rats may harm their male offspring's liver function.