research Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase
Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
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30 / 1000+ resultsresearch Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
research N1-acetylspermidine is a determinant of hair follicle stem cell fate
N1-acetylspermidine promotes hair follicle stem cell self-renewal.
research Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA
Altering SSAT affects fat metabolism and body fat in mice.
research Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
research Comparative characteristics of human stem cells
Human stem cells have diverse sources and potential uses in medicine.
research Differentiated approach to the implementation of preventive and anti-epidemic measures among military personnel based on the COVID-19 disease risk assessment scale
Tailoring COVID-19 measures to risk levels in the military improves health and readiness.
research The Pharma Market as Reflected by Patents
The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
research The early changes in mouse skin following topical application of a range of middle distillate oil products
Different oil products cause varying levels of skin irritation in mice, which could potentially lead to tumors.
research Bayesian measurement-error-driven hidden Markov regression model for calibrating the effect of covariates on multistate outcomes: Application to androgenetic alopecia
Model improves accuracy in predicting hair loss effects.
research Relevance of topical application of minoxidil laden nano-lipid for hair growth enhancement
The new minoxidil formula speeds up hair growth effectively.
research Seasonal and social correlates of changes in hair, skin, and scrotal condition in vervet monkeys (Cercopithecus aethiops) of Amboseli National Park, Kenya
Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.
research Using a capture–recapture method to assess the frequency of adverse drug reactions in a French university hospital
The study found that combining different databases gives a better estimate of drug side effects in hospitals.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research A Study of the androgen receptor gene polymorphism and the level of expression of the androgen receptor in androgenetic alopecia among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research Interventions for morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Interventions for alopecia areata
Current treatments for alopecia show no significant long-term benefits.
research Psychosocial Aspects of Skin Conditions and Diseases
Skin conditions can cause significant psychological distress, so addressing mental health is crucial for improving quality of life.
research A randomized, single-blind trial of 5% minoxidil foam once daily versus 2% minoxidil solution twice daily in the treatment of androgenetic alopecia in women
5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
research Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat
Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
research Complex Regional Pain Syndrome Type I : measurements and treatment
CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.
research Hair Follicle Transplantation on Scar Tissue
Hair follicle transplantation can hide scars but often needs more than one surgery for better results.
research Alopecia in Rhesus macaques correlates with immunophenotypic alterations in dermal inflammatory infiltrates consistent with hypersensitivity etiology
Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
research Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
research Polymorphism of genes in patients with new coronavirus infection COVID-19
Genetic differences affect COVID-19 severity and treatment effectiveness.
research Study of some pharmacotechnological, physico-chemical and pharmacognostic properties of common fennel (Foeniculum vulgare) fruit
Common fennel fruits can be effectively used to make medicines for better digestion.
research Systematic review: interventions in sickle cell disease-related priapism in reducing overall morbidity, recurrence, and side effects
More research is needed to find effective treatments for sickle cell disease-related priapism.
research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning
Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.
research Prevalence and associated factors of skin cancer in aged nursing home residents: A multicenter prevalence study
Skin cancer is common in elderly nursing home residents, with risk factors including being male, having light skin, outdoor work history, and smoking. Regular skin checks are recommended.
research Treatment of moderate-to-severe alopecia areata in adolescents with baricitinib: A retrospective review of 29 patients
Baricitinib helped most teenagers with severe hair loss regrow hair and had mild side effects.