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Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Early hormones shape sex-specific differences in rat glands.

PCOS is influenced by genetics and lifestyle, causing hormonal imbalances and health risks like diabetes and infertility.

PCOS is influenced by genetics and lifestyle, causing hormonal imbalances and health risks like diabetes and infertility.

Restoring nerve-macrophage communication may help treat autoimmune diseases.

Sex hormones influence immune responses and may help treat diseases.

New therapies targeting skin neuroimmune interactions could treat neuropathic pain.

Improving nerve and immune interactions may help heal chronic wounds.

Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.

Targeting specific biomarkers and immune signals is more effective and safer for treating inflammatory skin diseases.

Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Regulatory T cells and mesenchymal stem cells work together to prevent immune system overreactions and tissue damage.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

New diabetes tech and therapies improve care for endocrine disorders.

Age-related immune changes worsen Parkinson's disease, suggesting new treatment strategies.

Obesity may weaken the immune system and increase cancer risk.

Immune cells help keep skin healthy and repair it, but imbalance can cause disease.

Immunotherapy for cancer caused a patient to develop a condition affecting hormone production, requiring ongoing hormone replacement therapy.

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Neurotrophins are important for hair growth and response to stress.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.