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Parry–Romberg Syndrome can involve the brain even without obvious symptoms, and a new diagnostic framework is suggested for early detection.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.

Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.

Many patients experience long-lasting symptoms like fatigue and pain after COVID-19, regardless of initial disease severity.

Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.

Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.

Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.

Targeting endolysosomes may help treat COVID-19.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.

Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.

Adult stem cells are effective and ethically acceptable for treating various diseases.

Itchy scalp is common, linked to various conditions, and hard to treat effectively.

Goats with BSE or scrapie show varying symptoms, and using only clinical signs may not detect all scrapie cases.

Improving CRISPR/Cas systems can make gene editing more efficient and precise.

Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.

Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.

Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.

Caffeine can boost health but may cause side effects like high blood pressure and migraines.

Hydrogel composites are promising for treating chronic diabetic ulcers due to their versatility and effectiveness.

Controlling transposable elements is crucial for successful tissue regeneration.

Psychological stress can worsen skin conditions like psoriasis and acne.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.

Natural products may help treat Non-Small Cell Lung Cancer by causing cancer cell death through ferroptosis.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

Mesenchymal stem cells and their vesicles may effectively treat skin diseases, but more research is needed.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.