research Comment on Current Investigations into the Postfinasteride Syndrome
Finasteride is effective for hair regrowth, but some believe it may cause persistent symptoms due to psychological factors.
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research Phenotypic heterogeneity in human genetic diseases: ultrasensitivity-mediated threshold effects as a unifying molecular mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing ‘the Big Eight Strikes’
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle
The research found new potential mechanisms in mouse hair growth by studying RNA interactions.
research The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research The Impact of the 5α-Reductase Inhibitors (5α-RIs) on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research The Post-finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research The effects of fulvic acids and low-level laser therapy on orthodontic retention in rats
Low-level laser therapy reduces orthodontic relapse in rats, but fulvic acids do not.
research Whole Tooth Regenerative Therapy Using a Bioengineered Tooth Germ
Bioengineered teeth could replace damaged teeth and restore oral functions.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research The Possible Association of Female Pattern Hair Loss and Alteration in Serum Cholecalciferol Level
Low vitamin D levels can significantly contribute to hair loss, especially in women aged 35-45. Correcting these levels early may help prevent and treat this condition.
research TERAPINĖS BOTULINO NEUROTOKSINO A PANAUDOJIMO GALIMYBĖS
Botulinum neurotoxin A is effective and safe for treating various conditions, but more clinical trials are needed to fully assess its benefits and risks.
research Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia
Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
research Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment
Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
research Cardiovascular effects of hormone therapy for prostate cancer
Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
research Proopiomelanocortin (POMC) and Psychodermatology
Psychological stress can worsen skin conditions like psoriasis and acne.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Techniques and Applications of Lower Extremity Feminization and Masculinization
More research is needed to improve lower body gender affirmation techniques.
research Association between energy-adjusted dietary inflammatory index and sleep quality disorders: a cross-sectional study on fasa adult cohort
Improving diet may help manage sleep disorders.
research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Bioprinting is improving skin models for better testing of skin diseases without using animals.
research Topical gabapentin and its relation to cutaneous innervation in symptomatic lymphocytic primary cicatricial alopecia
Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.
research Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures
Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report
Vitamin D supplements may reduce hair-pulling in people with Trichotillomania.
research Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
research Female pattern alopecia: current perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women -A Nationwide Population-Based Cohort Study in Taiwan
Women with hyperandrogenism, especially those with PCOS, are more likely to have psychiatric disorders.