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Women with PCOS may have a higher risk of Alzheimer's disease.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.

New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.

People with androgenetic alopecia often experience more anxiety, depression, and lower self-esteem.

Finasteride use may increase suicidality risk, especially in young men.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Progesterone and testosterone protect brain cells from damage through specific pathways.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Psychological stress can worsen skin conditions like psoriasis and acne.

24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.

Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.

Higher doses of 5α-reductase inhibitors may lower mortality risk, but low doses increase it.

Women with PCOS have distinct retinal changes compared to healthy women.

Post-finasteride syndrome is rare but serious and should be taken seriously.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Medications for BPH can have significant side effects, so understanding these risks is important for treatment decisions.

Mitotane changes steroid breakdown, affecting cortisol availability.

Androgens improve memory in adolescent male rats by acting on brain receptors.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.

Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.

Finasteride may increase the risk of suicidality and depression, especially in younger people.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.