February 2026 in “Indian Dermatology Online Journal” This article discusses the use of oral tofacitinib in treating a 48-year-old woman with refractory Lichen Planus Pigmentosus (LPPigm) and coexisting Frontal Fibrosing Alopecia (FFA). The patient, who had not responded to previous treatments, showed significant improvement with tofacitinib, experiencing near-complete resolution of hyperpigmentation and cessation of hairline recession over 18 months. The treatment was well-tolerated with no adverse effects, and the patient remained in remission one year after stopping the medication. The study suggests that tofacitinib could be a promising treatment for these challenging conditions, although further research is needed to confirm its efficacy and safety.
January 2022 in “Drugs of Today” 8 citations
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December 2019 in “Molecular genetics and metabolism reports” Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.
1 citations
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June 2019 in “Current developments in nutrition” A combination of arginine silicate complex and magnesium biotinate improves hair and nail growth in rats.
30 citations
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December 2021 in “Frontiers in Microbiology” Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.
January 2001 in “Clinical and Experimental Dermatology” A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
June 2023 in “NILES Journal forGeriatric and Gerontology/NILES Journal for Geriatric and Gerontology” Oral tranexamic acid is a safe and effective treatment for melasma.
10 citations
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May 2020 in “Advances in Polymer Technology” Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
July 2024 in “Biomolecular and Health Science Journal” Mycophenolic acid effectively improved hair and nail growth in a lupus patient.
February 2024 in “Current Bioactive Compounds” The new gel formulation effectively delivers Finasteride for hair growth treatment without skin irritation.
3 citations
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February 2024 in “Journal of the American Academy of Dermatology” Topical tofacitinib cream may help treat certain hair loss conditions with fewer risks.
13 citations
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February 2017 in “Clinical rheumatology” Tofacitinib may help treat nail dystrophy, especially when other treatments fail.
3 citations
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January 2019 in “Annals of dermatology/Annals of Dermatology” Hydroxychloroquine effectively treated twenty-nail dystrophy in a patient with alopecia areata.
2 citations
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September 2024 in “Journal of Dermatological Treatment” Combining compound glycyrrhizin with minoxidil is more effective for alopecia areata than minoxidil alone.
May 2024 in “Indian Journal of Pharmacology” Tofacitinib effectively regrew scalp hair in an 11-year-old girl with alopecia areata.
December 2022 in “Cosmetics” The food supplement improved hair growth and strength in people with a certain type of hair loss and had no major side effects.
3 citations
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January 2000 in “Current Medical Research and Opinion” Eflornithine HCl 13.9% cream is safe for skin use with mild, temporary irritation.
Liposomes with minoxidil and PEP penetrate skin slowly but reach deeper layers than foam.
December 2025 in “International Journal of Molecular Sciences” Bacopa procumbens extract may help protect the brain in Parkinson's disease.
January 2026 in “Advanced Healthcare Materials” Stevioside-based microneedles improve minoxidil delivery for effective hair growth treatment.
3 citations
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December 2021 Niosomes are a promising method for delivering drugs directly to targeted areas in the body.
7 citations
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May 2022 in “International Journal of Environmental Research and Public Health” Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.
1 citations
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February 2020 in “PubMed” The topical solution improved hair density and appearance in men with androgenetic alopecia.
7 citations
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December 2021 in “Pharmaceutics” The nanoemulsion with garlic oil, apple cider vinegar, and minoxidil could effectively treat alopecia areata.
April 2015 in “Journal of Nutritional Therapeutics” Looser dietary restrictions can improve growth and reduce illness in methylmalonic acidemia patients.
78 citations
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March 2017 in “JAMA Dermatology” Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.
50 citations
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May 1985 in “The journal of pediatrics/The Journal of pediatrics” Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.
September 2025 in “Pharmaceutics” Quercetin nanocrystal gel shows promise for hair regrowth in androgenetic alopecia.