10 citations
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October 2016 in “Experimental Dermatology” Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
7 citations
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January 2022 in “Anais Da Academia Brasileira De Ciencias” Essential oils from Hedychium spicatum have potential for developing natural drugs with pain-blocking, fever-reducing, anti-inflammatory, and antioxidant properties.
6 citations
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January 2016 in “Dermatology Review” Stem cells show promise for treating skin conditions and aiding healing.
5 citations
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May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
5 citations
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December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
1 citations
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July 2025 in “Barrier Immunity” A holistic approach is crucial for treating skin disorders and restoring barrier function.
August 2024 in “Revista Científica Multidisciplinar Núcleo do Conhecimento” Malassezia restricta may be linked to intestinal diseases like Crohn's and ulcerative colitis.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
67 citations
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November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
18 citations
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August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
16 citations
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May 2011 in “The Journal of clinical investigation/The journal of clinical investigation” Some skin tumors may start from hair follicle stem cells.
13 citations
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April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
1 citations
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December 2024 in “Journal of Cutaneous Medicine and Surgery” AI is useful for diagnosing skin diseases but has limitations to consider before widespread use.
July 2023 in “Nature Genetics” Researchers identified key cell types and genes involved in hair and skin diseases.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
411 citations
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April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
169 citations
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January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
82 citations
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March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
80 citations
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April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
46 citations
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
42 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
37 citations
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August 2019 in “Frontiers in Microbiology” Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
17 citations
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March 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
15 citations
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May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
14 citations
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June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.