287 citations
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March 1999 in “The Plant Journal” Microtubules help control the direction and stability of root hair growth in Arabidopsis thaliana.
260 citations
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January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
166 citations
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November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
120 citations
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May 2012 in “Experimental Cell Research” VEGF promotes hair follicle cell growth through the VEGFR-2/ERK pathway.
112 citations
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January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
106 citations
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June 2009 in “BMC Genomics” Sea cucumbers have unique genes that help them regenerate their intestines.
105 citations
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December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
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December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
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March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
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March 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered scaffolds help heal skin wounds, but perfect treatments are still needed.
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October 2011 in “Clinica Chimica Acta” Hot water and UV exposure reduce hair cortisol levels, with the back of the head showing the most consistent levels.
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August 2019 in “Cell Proliferation” Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.
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April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
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October 2020 in “Frontiers in Pharmacology” Targeting endolysosomes may help treat COVID-19.
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August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
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August 2012 in “Differentiation” Mouse genital development depends on male or female hormones for specific features.
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April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
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January 2007 in “PubMed” Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.
50 citations
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February 2013 in “BMC evolutionary biology” Cetaceans lost hair due to changes in the Hr and FGF5 genes.
49 citations
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July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
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August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
49 citations
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November 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor helps control skin cell growth and hair development.
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April 2009 in “Journal of anatomy” Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
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January 2023 in “New Phytologist” FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.
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June 2024 in “Journal of Cellular and Molecular Medicine” Natural antioxidants may help prevent hair loss by reducing oxidative stress.
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January 2020 in “Journal of Experimental Botany” Moderate water stress helps rice form rhizosheaths by affecting hormone responses, which may aid in breeding drought-resistant rice.
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December 2017 in “Stem Cells Translational Medicine” We need to understand more about regeneration to improve human tissue healing.
29 citations
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January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
28 citations
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September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.