16 citations
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September 2015 in “International Journal of Molecular Sciences” A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
15 citations
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February 2020 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is crucial for healthy skin barrier function.
12 citations
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September 2022 in “Foods” Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.
11 citations
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November 2021 in “JBMR plus” The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
9 citations
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August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
8 citations
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December 2024 in “Frontiers in Medicine” Damaged skin has a weakened barrier, making it more vulnerable to substances and inflammation.
7 citations
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October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
6 citations
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January 2024 in “Cancers” Antiandrogens don't help with COVID-19 and aren't recommended.
6 citations
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July 2021 in “Frontiers in Genetics” A gene variant causes a skin and hair disorder by disrupting protein balance.
5 citations
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December 2022 in “Viruses” Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.
5 citations
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September 2024 in “Life” Natural products can safely and effectively treat various human diseases.
5 citations
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June 2022 in “Biophysical Journal” TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
2 citations
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December 2025 in “Cosmetics” Proper scalp care can improve hair health and delay ageing signs.
2 citations
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November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
March 2026 in “Virulence” Vimentin and keratin help viruses spread and could be targets for antiviral treatments.
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
January 2025 in “International Journal of Nanomedicine” Rosemary-based gel with metformin may effectively treat hair loss like minoxidil.
July 2025 in “International Journal of Trichology” Biological factors are crucial for developing new hair restoration treatments.
Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
29 citations
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January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
14 citations
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June 2022 in “BMC genomics” Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
14 citations
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March 2016 in “Mechanisms of Development” Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
8 citations
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June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
467 citations
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May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
200 citations
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March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
81 citations
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February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
36 citations
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August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.