35 citations
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October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
32 citations
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June 2024 in “Pharmaceutics” Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.
24 citations
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September 2014 in “PloS one” Thyroid hormone receptors are essential for hair growth and wound healing.
21 citations
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December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
18 citations
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June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
15 citations
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April 2017 in “Hormones” Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
14 citations
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November 2024 in “International Journal of Molecular Sciences” YAP and TAZ proteins control skin cell growth and repair.
14 citations
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February 2024 in “Biomolecules” TRPV channels are important in osteoarthritis and could be key to new treatments.
14 citations
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March 2022 in “Journal of Biomedical Science” Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
14 citations
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July 2019 in “Journal of Investigative Dermatology” Integrin-linked kinase is crucial for melanoblasts to properly colonize the skin.
12 citations
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January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
10 citations
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August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
10 citations
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August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
9 citations
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October 2025 in “MedComm” PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
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July 2024 in “JAAD reviews.” Extracellular vesicles show potential in dermatology, but more research is needed for validation.
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November 2022 in “International Journal of Molecular Sciences” The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.
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July 2022 in “International Journal of Molecular Sciences” Prenatal THC exposure may harm ovarian health and fertility.
7 citations
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September 2024 in “International Journal of Molecular Sciences” PCOS involves high 11-oxygenated androgens and BPA may worsen it, while IH is not inflammatory.
7 citations
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January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
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April 2021 in “Journal of Lower Genital Tract Disease” Erosive lichen sclerosus is a distinct subtype with specific skin features, and treatment led to complete resolution in half of the cases.
6 citations
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July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
6 citations
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September 2023 in “International journal of molecular sciences” Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
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August 2023 in “Fertility and Sterility” The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
6 citations
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December 2022 in “International Journal of Molecular Sciences” EZH2 is crucial for uterine gland development and female fertility.
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April 2022 in “Biomedicine & pharmacotherapy” Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
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January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
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May 2024 in “Molecules” Glycyrrhetinic acid from licorice may help treat acne by reducing inflammation and oil production.
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April 2024 in “Biology” Improving human hair follicle models is crucial for better hair loss treatments.
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November 2022 in “Diversity” South African wild foods may help prevent cardiovascular disease.