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April 2018 in “Frontiers in endocrinology” Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
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April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
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August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
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June 2023 in “Biomedicines” Men generally face more severe COVID-19 outcomes than women, partly due to hormonal differences.
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November 2024 in “International Journal of Molecular Sciences” COVID-19 may worsen Parkinson's disease by affecting certain brain proteins.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
276 citations
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186 citations
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February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
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July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
63 citations
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September 2020 in “Frontiers in Microbiology” Probiotics show promise for health benefits but need more research to understand how they work.
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November 2024 in “International Journal of Molecular Sciences” Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
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October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
34 citations
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August 2015 in “Frontiers in Behavioral Neuroscience” Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.
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December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
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April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
14 citations
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May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
13 citations
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February 2021 in “Brain Sciences” Androgens improve memory in adolescent male rats by acting on brain receptors.
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October 2019 in “Oncology Reports” The link between anabolic agents and colorectal cancer risk is unclear.
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July 2024 in “Biomimetics” Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
10 citations
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March 2024 in “Frontiers in Bioengineering and Biotechnology” Photothermal hydrogels can kill bacteria and help heal tissue using light-converted heat.
9 citations
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April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
8 citations
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February 2022 in “Scientific Reports” Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.
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January 2021 in “Fermentation” Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
7 citations
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December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
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January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
6 citations
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May 2023 in “European journal of pharmaceutical sciences” Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
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August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.