January 2020 in “Acta Scientiae Veterinariae” A dog's chronic bite wound healed successfully using a mix of herbal gel, low power laser, and ozone therapy.
January 2024 in “Surgical & Cosmetic Dermatology” Exosomes may help treat skin diseases and improve skin rejuvenation.
Eclipta alba can be used in products to treat hair loss.
April 2026 in “Preprints.org” Bioavailable quercetin may help improve aging signs by positively affecting gut health.
April 2025 in “Archives of Dermatological Research” H19 may help prevent hair loss by keeping hair cells young.
21 citations
,
June 2009 in “Mammalian genome” A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.
92 citations
,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
41 citations
,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
5 citations
,
January 2024 in “Reproductive Medicine and Biology” Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.
December 2024 in “Stem Cell Research & Therapy” ZO-1 helps hair follicle stem cells renew better by changing their structure.
April 2020 in “Journal of the Endocrine Society” Type 3 acromegaly patients have more health issues and higher death risk.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
176 citations
,
January 2013 in “Proceedings of the National Academy of Sciences” BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
54 citations
,
December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
51 citations
,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
50 citations
,
September 2023 in “Biomarker Research” S100A6 is important for cell functions and can help diagnose and treat diseases.
49 citations
,
May 2020 in “Journal of Clinical Investigation” Exosomes are crucial for protecting sensory hair cells in the inner ear.
36 citations
,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
32 citations
,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
29 citations
,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
29 citations
,
October 2010 in “Journal of Investigative Dermatology” Activating Kras in mouse skin causes excess skin and hair loss.
17 citations
,
May 2013 in “Journal of Investigative Dermatology” Mutations in β1 integrins cause embryonic death but have milder effects on skin.
15 citations
,
February 2020 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is crucial for healthy skin barrier function.
13 citations
,
July 2020 in “Stem Cell Research & Therapy” Young donor, early passage stem cells have the highest stemness.
13 citations
,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
9 citations
,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
7 citations
,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
3 citations
,
January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.