research Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker
Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
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research Combined drug triads for synergic neuroprotection in retinal degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
research Effects of SLC45A2 and GPNMB on Melanin Deposition Based on Transcriptome Sequencing in Chicken Feather Follicles
SLC45A2 and GPNMB genes help control chicken feather color by promoting melanin.
research Lupeol: an updated review utilizing AI-assisted predictive tools for enhanced therapeutic insights into lupeol’s potential for alopecia management
Lupeol shows promise for hair growth but needs better absorption and safety testing.
research Dynamic Transcriptome Profile Analysis of Mechanisms Related to Melanin Deposition in Chicken Muscle Development
Key genes influence melanin in chicken muscles, affecting their value.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
research ENZYMES
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Exploring the molecular mechanism of Polygonum multiflorum in treating androgenic alopecia based on the methods of bioinformatics and molecular docking
Polygonum multiflorum may help treat hair loss but can be toxic to the liver.
research Intrinsic and Extrinsic Factors Associated with Hair Graying (Canities) and Therapeutic Potential of Plant Extracts and Phytochemicals
Plant extracts may help prevent or reverse hair graying.
research The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19
Cepharanthine shows promise as a COVID-19 treatment.
research Gene Expression Profiles of Melanocytes Over-Expressing miR-5110 in Alpaca
miR-5110 affects alpaca pigmentation by altering specific gene expressions.
research The Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma: Prognostic or Therapeutic?
LncRNAs may help improve brain cancer treatment and diagnosis.
research Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells
Scientists created feather buds in lab-grown chick skin using specific cell interactions.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrosis and cancer.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research 527 PTEN is a master driver of healing inhibition in venous leg ulcers by targeting immune response, angiogenesis and lymphangiogenesis
Targeting PTEN can improve healing in venous leg ulcers.
research Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing
Stem cell-derived vesicles show promise for healing diabetic wounds.
research Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications
Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
research Recent Progress in Health Benefits of Hederagenin and Its Glycosides
Hederagenin shows promise for cancer and inflammation treatment but needs modifications to improve effectiveness.
research Aging in the sebaceous gland
Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
research The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth?
Understanding EGFR roles could lead to new hair loss treatments.
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging
Epigenetic and metabolic changes affect stem cell function and aging in skin.
research Inflammatory auxo-action in the stem cell division theory of cancer
Chronic inflammation can cause cancer by making stem cells divide and mutate.
research Concise Review: Translating Regenerative Biology into Clinically Relevant Therapies: Are We on the Right Path?
We need to understand more about regeneration to improve human tissue healing.
research Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models
Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.