research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Targeting cellular senescence may improve skin aging and disorders.
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150-180 / 1000+ resultsresearch Pre‐clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer
Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.
research Role of Polyphenols in Dermatological Diseases: Exploring Pharmacotherapeutic Mechanisms and Clinical Implications
Polyphenols may help treat skin diseases due to their anti-inflammatory and antioxidant effects.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Regulatory T cells in skin regeneration and wound healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism
The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
research Highlights from the Field of Pediatric Dermatology Research from the 2023 PeDRA Annual Conference
The conference highlighted new treatments and research in pediatric skin conditions, emphasizing collaboration and innovation.
research Active Compounds with Medicinal Potential Found in Maxillariinae Benth. (Orchidaceae Juss.) Representatives—A Review
Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research Sinergitas Efek Kombinasi Ekstrak Daun SirsaK (Annona muricata Linn) Dengan Doksorubisin Pada Sel Kanker Payudara MCF-7
Combining soursop leaf extract with doxorubicin may improve breast cancer treatment and reduce side effects.
research The Roles of EDA2R in Ageing and Disease
EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.
research The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions
Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research 879 Molecular network of Smads and Id2 genes in hair follicle stem cells regulation
The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.
research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model
Triptolide effectively and safely reduces actinic keratosis lesions in mice.
research 883 Hair follicle bulb developed as 3D scaffold free microtissue
Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.
research 881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration
research Acne
Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.
research Cutaneous Reactions to Drugs
Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
research Topical Metformin In Dermatology: A Narrative Review Of Efficacy And Formulation Approaches
Topical metformin shows promise for treating skin conditions like acne and psoriasis.
research Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions
Personalized treatments for hair loss focus on specific genetic and biological pathways.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research Does a male polycystic ovarian syndrome equivalent exist?
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research From causes of aging to death from COVID-19
Older age and related diseases increase COVID-19 risk, but anti-aging treatments might help.
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts
Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.