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Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Presurgical models can effectively and affordably screen cancer prevention agents.

New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

Immune checkpoint inhibitors can cause scalp inflammation and hair follicle issues.

New progesterone-based compounds can block male hormones.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.

Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

A young woman with severe symptoms of CPAN improved with intensive treatment but needed a leg amputation.

Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.

Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.

Ginkgolide B and bilobalide help mink hair grow by making skin cells healthier and boosting a key growth protein.

Setipiprant did not significantly improve hair growth in men with hair loss.

Hoxc13 regulates specific hair protein genes on mouse chromosome 16.

The medicine Cyclosporin A might cause excessive hair growth by reducing a protein that controls hair growth.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Janus kinase inhibitors are effective and safe for treating alopecia areata.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

JAK inhibitors can be safely used in alopecia areata patients with latent hepatitis B or tuberculosis, with proper monitoring.

JAK inhibitors are more effective and safer for treating alopecia areata than dupilumab and apremilast.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.