49 citations
,
August 2016 in “Aesthetic Surgery Journal” Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
59 citations
,
July 2015 in “Journal of innovative optical health sciences/Journal of innovation in optical health science” Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
4 citations
,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
1 citations
,
August 2019 in “Journal of Dentistry Indonesia” A 645-nm diode laser effectively penetrates swine soft tissues, suggesting predictable therapeutic effects.
1 citations
,
January 2017 in “Springer eBooks” Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
90 citations
,
November 2014 in “Journal of Biomedical Optics” Silver nanoparticles can penetrate porcine skin up to about 15.6 μm, possibly through hair follicles.
316 citations
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
19 citations
,
December 2013 in “European journal of pharmaceutics and biopharmaceutics” Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
7 citations
,
October 2024 in “Drug Delivery and Translational Research” A 4% nanoparticle concentration and 4 Hz massage improve drug delivery into hair follicles.
6 citations
,
December 2018 in “International Journal of Cosmetic Science” CARB is a strong barrier in human hair that prevents dye penetration.
April 2024 in “Cosmetics” Different oils affect hair flexibility and strength, with their impact varying on whether hair is virgin or bleached.
2 citations
,
November 2025 in “Pharmaceutics” Moderately lipophilic dyes penetrate skin deeply, while highly hydrophobic or lipophilic dyes stay on the surface.
26 citations
,
December 2009 in “Laser Physics” Caffeine from shampoo penetrates hair follicles quickly and stays for at least 24 hours.
61 citations
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May 2016 in “Scientific reports” The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
12 citations
,
June 2011 in “Journal of applied polymer science” L-phenylalanine and hydrolyzed eggwhite protein deeply penetrate human hair.
8 citations
,
April 2012 in “Laser Physics Letters” Antiseptic particles penetrate deeper into hair follicles than non-antiseptic ones.
1 citations
,
April 2024 in “Journal of Drug Delivery Science and Technology” Microneedles combined with conventional therapies show promise in treating alopecia areata.
39 citations
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November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
21 citations
,
November 2020 in “European Journal of Pharmaceutics and Biopharmaceutics” Low-frequency skin massage helps nanoparticles penetrate hair follicles better.
81 citations
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October 2023 in “Bioactive Materials” 3D-printed microneedles improve drug delivery and diagnostics but face scalability and regulatory challenges.
15 citations
,
April 2021 in “International Journal of Pharmaceutics” Smaller mesoporous nanoparticles can improve the effectiveness of topical drugs by penetrating skin furrows.
September 2023 in “Biomedical Optics Express” New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
94 citations
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September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
71 citations
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March 2016 in “PubMed” Smaller particles improve drug delivery through the skin.
55 citations
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June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
62 citations
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November 2016 in “Nanoscale” Medium to larger nanogels effectively deliver drugs through hair follicles when heated.
43 citations
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November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
20 citations
,
January 2015 in “Polish Journal of Pathology” Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.
14 citations
,
March 2020 in “Scientific Reports” Using dual-frequency ultrasound with microbubbles can potentially improve the delivery of hair growth treatment through the skin and enhance hair growth.
6 citations
,
May 2022 in “Pharmaceutics” Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.