research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege
Hair follicle cells help protect against immune attacks by regulating T-cell activity.
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960-990 / 1000+ resultsresearch Study the Effect of Inflammatory Cytokines on Hair Loss
Inflammation is linked to hair loss.
research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research Discoid lupus alopecia complicated by frontal fibrosing alopecia on a background of androgenetic alopecia
Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
research Breast Implant-Associated Immunological Disorders
Breast implants are linked to autoimmune symptoms, with over half of patients feeling better after removal, but the exact cause is unclear and may involve bacterial biofilm.
research [Hidradenitis suppurativa - symptoms, diagnostics, and therapy].
Hidradenitis suppurativa is a chronic skin condition causing painful lumps and scarring, often triggered by smoking and obesity, and requires varying treatments based on severity.
research Isotretinoin으로 치료한 농양성 천굴성 두부모낭주위염
Isotretinoin treatment improved scalp condition and stopped hair loss.
research 496 Understanding the mechanism of action of secukinumab using lesional hidradenitis suppurativa skin organ culture
Secukinumab reduces immune activity in hidradenitis suppurativa skin.
research Author response: Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
Sphingosine 1-phosphate affects inflammation and gene expression in different aorta cells.
research Adenohypophysitis Associated with Sebaceous Gland Atrophy in a Dog
A dog had a rare skin condition linked to gland and pituitary issues.
research Epidermal γδ T cells, CD8 T cells and macrophages are increased in number in alopecia areata and express BST2 as part of an interferon-driven antiviral gene signature
In alopecia areata, certain immune cells increase and express a protein linked to immune activation.
research The clinicopathological spectrum of preclinical folliculitis keloidalis with correlation to its dermoscopic features: a cross‐sectional analytical study
Early detection and treatment of folliculitis keloidalis can prevent disease progression.
research Dexmedetomidine-Loaded Hydrogel Microneedles Alleviate Acute Inflammatory Visceral Pain in Mice
Dexmedetomidine-loaded microneedles effectively reduce pain without sedation.
research Clinical Evaluation of the MIRA Technique in Cellulite Treatment: A Retrospective Case–Control Study
The MIRA technique improves cellulite treatment results and patient satisfaction.
research Lack of efficacy of apremilast in 9 patients with severe alopecia areata
Apremilast did not work for treating severe alopecia areata.
research ANTI-INFLAMMATORY ACTIVITY OF PLATELET-RICH PLASMA TREATMENT IN THE INFLAMMATION MANAGEMENT OF KNEE OSTEOARTHRITIS: EXPERIMENTAL STUDY
Platelet-rich plasma treatments reduce knee osteoarthritis inflammation, with pure PRP being more effective.
research Análise comparativa de 126 pacientes com lúpus discoide: perfil clínico e imunológico dos pacientes com lesões no couro cabeludo
Scalp lesions in discoid lupus are more common in women and linked to other autoimmune diseases.
research IL-17 Expression in the Perifollicular Fibrosis in Biopsies From Lichen Planopilaris
Blocking IL-17 might help treat the hair loss condition Lichen planopilaris.
research Hyperadrenocorticism associated with adrenocortical tumor or nodular hyperplasia of the adrenal gland in ferrets: 50 cases (1987-1991)
Diagnosis of adrenal issues in ferrets should use symptoms, ultrasound, and surgery, not ACTH tests.
research Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages
Activating liver X receptors can reduce fibrosis by stopping certain immune cells from releasing harmful proteins.
research Rare Gli1+ perivascular fibroblasts promote skin wound repair
Rare Gli1+ fibroblasts are crucial for skin wound healing.
research What causes acne inversa (or hidradenitis suppurativa)? – the debate continues
The exact cause of hidradenitis suppurativa is still unknown.
research Localized Scleroderma morphea-like in a cat.
The cat's skin condition was resistant to treatment and did not improve.
research Lipid Modulation and Systemic Inflammation
Dietary lipids affect inflammation and are crucial for normal cell function and immune health.
research 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq
The study identified key immune cell differences between mild and severe alopecia areata.
research WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling
Targeting Hedgehog signaling may help treat ligamentum flavum fibrosis.
research Diagnostic dilemma: Multiple Autoimmune Syndrome versus incomplete Graham-Little-Piccardi-Lassueur Syndrome overlap mixed connective tissue disease
The case shows how hard it is to tell apart Multiple Autoimmune Syndrome from other similar autoimmune conditions, but correct diagnosis is key for treatment to work.
research Multi-omics analysis unveils the role of cancer-associated fibroblasts in cutaneous squamous cell carcinoma
Cancer-associated fibroblasts promote tumor growth in skin cancer.
research Çocukta obezite ile birlikte lipoödematöz skalp
An 11-year-old obese girl was diagnosed with lipedematous scalp, a condition with swollen scalp tissue usually found in adult women.
research A 25-year-old female with a variable presentation of MCTD-A case report
Careful diagnosis and management of MCTD are crucial due to potential severe complications.