June 2026 in “International Journal of Drug Delivery Technology” Androgenetic alopecia (AGA) involves complex mechanisms including genetic and epigenetic factors, androgen sensitivity, and follicular miniaturization. Traditional treatments like minoxidil and finasteride have limited effectiveness and can cause side effects. Advanced topical delivery systems using polymeric micelles offer a promising alternative. These micelles, formed from amphiphilic block copolymers, provide enhanced drug encapsulation and targeted delivery to hair follicles, improving retention and release while minimizing systemic exposure. This approach can potentially revolutionize AGA treatment by inducing hair growth phases, promoting angiogenesis, and allowing for combination therapies with better efficacy and patient adherence.
January 2009 in “Chinese Journal of Drug Application and Monitoring” Finasteride granules and tablets work the same in the body.
12 citations
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January 2018 in “Acta pharmaceutica sciencia” Solid lipid nanoparticles can improve how well drugs that don't dissolve in water work and are safe.
January 2025 in “Drug repurposing” New drug uses show promise but need more research.
25 citations
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July 2019 in “Journal of drug delivery science and technology” Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
140 citations
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January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
3 citations
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January 2006 in “Eclética Química” Three cost-effective methods accurately measure finasteride in pharmaceuticals, better than current techniques.
![Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)](/images/research/d743d32f-3115-48ff-9697-2f2d56130701/small/14175.jpg)
6 citations
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September 2015 in “Journal of Medicinal Chemistry” The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
19 citations
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November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
2 citations
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January 1995 in “Cahiers de droit européen” Phospholipid-polymer hybrid nanoparticles could help treat hair loss by delivering quercetin effectively.
24 citations
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June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
9 citations
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August 2020 in “International Journal of Molecular Sciences” New compounds may help treat heart disease by activating specific potassium channels.
April 2026 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA” The gel effectively delivers EGCG through the skin, improving its absorption.
2 citations
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May 2021 in “Research Square (Research Square)” Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
29 citations
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February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications” New method detects finasteride in plasma quickly and accurately without clean-up.
2 citations
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May 2021 in “Neuropathology & applied neurobiology/Neuropathology and applied neurobiology” Correct diagnosis and treatment are crucial for effective management of lipid storage myopathies.
December 2025 in “Phytomedicine Plus” Combining herbal medicines with modern delivery systems may improve alopecia treatment.
46 citations
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October 2022 in “Biomaterials” November 2024 in “Advances in Pharmacology and Pharmacy” A reliable method was developed to measure Minoxidil and Tofacitinib in gel for hair loss treatment.
19 citations
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September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
2 citations
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December 2021 in “Korean Journal of Clinical Pharmacy” November 2025 in “Molecules” Microextraction techniques improve hormone testing while being environmentally friendly.
March 2026 in “Mini-Reviews in Medicinal Chemistry” Oral minoxidil can be improved for hair loss treatment with personalized strategies and new technologies.
Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.
39 citations
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August 2017 in “Colloids and Surfaces B: Biointerfaces” 50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
January 2016 in “International journal of advanced research in chemical sciences” A new method using NBD-CL can accurately and precisely measure finasteride in medicine, and could be used regularly for quality control in the industry.
4 citations
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January 2002 in “Indian Journal of Pharmaceutical Sciences” A new method accurately measures finasteride in tablets using color change and light absorption.
September 2023 in “Pharmaceuticals” Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
5 citations
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April 2024 in “Science China Materials” 
October 2025 in “Transplantation” Dissolving microneedles with finasteride improve drug delivery for hair loss treatment.