55 citations
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August 2024 in “Heliyon” Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
426 citations
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August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
9 citations
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January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
7 citations
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June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
7 citations
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March 2017 in “Experimental and Therapeutic Medicine” Hair follicle cells can help keep embryonic stem cells undifferentiated.
March 2026 in “Frontiers in Cell and Developmental Biology” Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
1 citations
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February 2023 in “ACS Biomaterials Science & Engineering” The new microwell device helps grow more hair stem cells that can regenerate hair.
550 citations
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December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
387 citations
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May 2019 in “International Journal of Molecular Sciences” Adipose-derived stem cells are promising for regenerative medicine due to their accessibility, versatility, and low risk of immune rejection.
344 citations
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June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
169 citations
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January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
52 citations
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October 2005 in “Journal of Investigative Dermatology” Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.
41 citations
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April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
34 citations
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January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
33 citations
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December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
26 citations
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September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
21 citations
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October 2009 in “Biochemical Engineering Journal” Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
19 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” MSC-sEVs may effectively treat chronic non-healing wounds.
15 citations
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December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
14 citations
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January 2014 in “Cells Tissues Organs” Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
12 citations
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September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
11 citations
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June 2005 in “Stem Cells and Development” Intestinal stem cells can help repair skin damage from radiation.
4 citations
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March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
3 citations
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August 2025 in “Stem Cell Research & Therapy” Adipose-derived stem cells show promise in treating hair loss by promoting hair regrowth and improving hair follicle function.
3 citations
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May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
2 citations
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November 2022 in “Journal of Biochemistry and Molecular Biology” Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
October 2025 in “International Journal of Molecular Sciences” Stem cells have great potential for treating various medical conditions.
June 2025 in “Cell Regeneration” Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.