6 citations
,
September 2022 in “Frontiers in pharmacology” Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
5 citations
,
October 2021 in “Dermatologic Surgery” Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
1 citations
,
July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
138 citations
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November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
8 citations
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August 2018 in “BMJ Case Reports” Pazopanib treatment caused rapid hair color loss, possibly indicating its effectiveness.
6 citations
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January 2018 in “International Journal of Dermatology” Repigmentation patterns in vitiligo depend on melanocyte source, lesion status, and therapy choice.
25 citations
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January 2013 in “Colloids and surfaces. B, Biointerfaces” Hair dye colors mainly target melanin granules in black hair.
7 citations
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August 2007 in “Journal of Biotechnology”
July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
December 2023 in “Journal of ethnopharmacology” Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
18 citations
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September 2016 in “International Journal of Molecular Sciences” Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The herbal hair dye is a safe, effective, and natural alternative to chemical dyes.
24 citations
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September 2008 in “Clinical and experimental dermatology” Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
39 citations
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August 2005 in “Dermatologic surgery” Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.
Trichopigmentation is a non-invasive, reversible treatment for hair loss that offers natural-looking results for both men and women.
1 citations
,
March 2025 in “Journal of Cosmetic Dermatology” Exosomes and laser therapy can help regrow and repigment hair.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” Microneedling with PRP effectively reduces facial pigmentation with minimal side effects.
June 2023 in “Pediatric investigation” A boy's scalp infection, usually found on the body, was effectively treated with antifungal cream.
April 2025 in “Health Science Reports” PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.
13 citations
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September 2022 in “Materials & design” The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.
July 2025 in “Dermatology Practical & Conceptual” Topical eyedrops may cause eyelash whitening and skin lightening around the eyes.
10 citations
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January 2010 in “Acta dermato-venereologica” Light therapy can effectively treat vitiligo and hair loss caused by a specific medication.
PMEE may help reverse greying hair by boosting melanin production.
10 citations
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July 2022 in “Journal of Cosmetic Dermatology” Medicago sativa extract may help treat vitiligo by enhancing skin and hair pigmentation.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
1 citations
,
July 2018 in “JAMA dermatology” Poliosis causes white hair patches due to lack of melanin.
5 citations
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September 2014 in “Journal of Pharmaceutical Sciences”
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The herbal hair dye with Barleria prionitis is a safe, effective, and natural alternative to chemical dyes.
2 citations
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January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
31 citations
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February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.