research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
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research Clinico-epidemiological study of alopecia areata
Alopecia areata mainly affects young people, often showing as patchy hair loss on the scalp.
research Early leonine facies with alopecia in a young man
A young man was diagnosed with trichoepitheliomas, causing thick skin and hair loss.
research Regarding prostate-specific antigen: let's not shoot the messenger
The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
research Overlap Between Ulerythema Ophryogenes and Keratosis Follicularis Spinulosa Decalvans: a Case Report
A 19-year-old male had two rare skin conditions causing scarring and permanent hair loss.
research PSA Test Sensitized by Finasteride
Finasteride improves prostate cancer detection in PSA test.
research Clinical Predictors of Outcome in Nonsegmental Vitiligo: A Prospective Cohort Study
Certain skin and family history markers predict vitiligo severity and treatment needs.
research Assessment of Efficacy and Safety Profile of Platelet Rich Plasma (PRP) Therapy with Derma Roller in the Treatment of Female Pattern Hair Loss
PRP therapy with a derma roller is a safe and effective treatment for female hair loss.
research Reversible Hyperpigmentation: A Diagnostic Dilemma
Vitamin B12 deficiency can cause reversible skin darkening.
research Creating slits to the right depth: Innovative use of micropore tape for depth control on an 18-gauge needle in hair restoration surgery
The document concludes that using micropore tape on an 18-gauge needle can control depth in hair restoration surgery, reducing scalp trauma and complications.
research Non-ablative radio frequency for the treatment of androgenetic alopecia
Non-ablative radio frequency can potentially increase hair count in men with androgenetic alopecia, but some may be bothered by the smell during treatment.
research 天然药物自组装纳米粒的形成机制、构建及性能评价
Natural product nanoparticles improve drug absorption but need better stability and production methods.
research Dissimilar effects of the hydrophilic carbon dots on the amyloid aggregation of two model proteins and the mechanism discussion
Hydrophilic carbon dots cause one protein to clump more and prevent another from clumping.
research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
research Crosstalk between vimentin and keratins in viral infection: Implications across the viral life cycle
Vimentin and keratin help viruses spread and could be targets for antiviral treatments.
research Matriptase-2, A Novel Suppressor of Hepcidin.
Matriptase-2 helps control iron levels by suppressing hepcidin, and its deficiency can cause iron-deficiency anemia.
research Diagnostic, Therapeutic, and Theranostic Multifunctional Microneedles
Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
research Nitrate‐inducible NIGT1 proteins modulate phosphate uptake and starvation signalling via transcriptional regulation of SPX genes
Nitrate helps plants manage phosphate uptake and starvation responses through NIGT1 proteins.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Sıçan Derisinde Vimentin, Desmin ve Laminin’in Dağılımı
Vimentin, desmin, and laminin help maintain rat skin structure.
research Ultrastructural Localization of S100A3, a Cysteine-rich, Calcium Binding Protein, in Human Scalp Hair Shafts Revealed by Rapid-freezing Immunocytochemistry
S100A3 protein is mainly found in specific parts of human hair cells.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma
Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.
research Heat shock protein 25 plays multiple roles during mouse skin development
research Crystallin Fusion Proteins Improve the Thermal Properties of Hair
Fusion proteins can protect hair from heat damage.
research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
research Human Hair Keratin‐Associated Proteins (KAPs)
Keratin-associated proteins are crucial for hair strength and structure.
research iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration
Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.