May 2026 in “SJ Gynecology and Obstetrics Africa” In a study of 100 young women aged 15–25 with polycystic ovary syndrome (PCOS) in India, 27% were found to have abnormal glucose tolerance, with 22% having impaired glucose tolerance (IGT) and 5% having diabetes mellitus. The study highlighted that abnormal glucose tolerance was more prevalent among women with higher BMI, central adiposity, a waist–hip ratio of ≥0.85, and a family history of diabetes. Additionally, conditions such as acanthosis nigricans, primary subfertility, and polycystic ovarian morphology were more common in those with IGT or diabetes. The findings suggest that a 75 g oral glucose tolerance test is useful for early detection of dysglycaemia in young women with PCOS, especially those with obesity or a family history of diabetes.
April 2024 in “International Journal of Advanced Multidisciplinary Research and Studies” Early investigation and a team approach are crucial for managing primary amenorrhea effectively.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
2 citations
,
January 2017 in “Cambridge University Press eBooks” Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.
22 citations
,
June 2007 in “Radiologia Medica” Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
8 citations
,
February 2025 in “Swiss Medical Weekly” Integrating best practices for steroid users in Swiss primary care is feasible and beneficial, but doping laws need change.
49 citations
,
January 2010 in “International Journal of Pediatric Endocrinology” The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
38 citations
,
December 2010 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
21 citations
,
February 2016 in “Reproductive Biomedicine Online” The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
3 citations
,
February 2017 in “Archives of Medical Science” Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
1 citations
,
January 2015 in “Case reports in endocrinology” Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.
September 2024 in “Reproduction and Fertility” New methods may speed up drug development for male subfertility.
49 citations
,
December 2007 in “Fertility and Sterility” Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
September 2022 in “Women's healthcare” PCOS is managed by lifestyle changes and personalized medication to improve symptoms and fertility.
November 2025 in “Gynecological Endocrinology” Effective PCOS management needs clear roles between primary and specialist care, digital tools, and patient education.
43 citations
,
October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
35 citations
,
January 2011 in “Clinical Endocrinology” Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.
13 citations
,
October 2011 in “Clinical Obstetrics and Gynecology” Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.
March 2024 in “Cleveland Clinic journal of medicine” Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.
January 2024 in “Women's health science journal” Hormonal imbalances are a key cause of missed menstrual periods in women.
257 citations
,
July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
103 citations
,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
38 citations
,
March 2020 in “Current Hypertension Reports” Reproductive factors can increase hypertension risk and affect cardiovascular health.
30 citations
,
June 2019 in “Frontiers in Endocrinology” The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.
30 citations
,
June 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
December 2023 in “Urogenital tract infection” Seminal bacteria can lower sperm quality in subfertile men.
September 2025 in “Tijdschrift voor Geneeskunde” Diagnosing thyroid disorders is complex and requires thorough testing due to nonspecific symptoms like hair loss.
Accurate diagnosis of PCOS requires comprehensive androgen measurement.
January 2025 in “PLoS ONE” ING5 is crucial for stem cell maintenance and preventing certain cancers.
9 citations
,
July 2022 in “International Journal of Molecular Sciences” Prenatal THC exposure may harm ovarian health and fertility.